Concept

Universal Darwinism

Related publications (32)

Advancing Cell-Free Synthetic Biology: From sustained PURE protein synthesis to an isothermal one-pot DNA replication system

One of the goals of synthetic biology is the development of an artificial cell. Building an artificial cell from scratch will provide a deeper understanding of fundamental mechanisms and models in biology and promises to contribute towards building novel p ...

EPFL2024

Glacier-Fed Stream Biofilms Harbor Diverse Resistomes and Biosynthetic Gene Clusters

Tom Ian Battin, Hannes Markus Peter, Susheel Bhanu Busi, Grégoire Marie Octave Edouard Michoud, Leïla Ezzat, Massimo Bourquin, Tyler Joe Kohler, Stylianos Fodelianakis, Paraskevi Pramateftaki, Vincent Henri De Staercke, Matteo Tolosano, Michail Styllas

Antimicrobial resistance is an omnipresent phenomenon in the anthropogenically influenced ecosystems. However, its role in shaping microbial community dynamics in pristine environments is relatively unknown. Antimicrobial resistance (AMR) is a universal ph ...

AMER SOC MICROBIOLOGY2023

Energy-harnessing problem solving of primordial life: Modeling the emergence of catalytic host-nested parasite life cycles

Christian Iseli

All life forms on earth ultimately descended from a primordial population dubbed the last universal common ancestor or LUCA via Darwinian evolution. Extant living systems share two salient functional features, a metabolism extracting and transforming energ ...

2023

Extra Newton: A First Approach to Noise-Adaptive Accelerated Second-Order Methods

Volkan Cevher, Kimon Antonakopoulos, Ali Kavis

This work proposes a universal and adaptive second-order method for minimizing second-order smooth, convex functions. Our algorithm achieves O(σ/T‾‾√) convergence when the oracle feedback is stochastic with variance σ2, and improves its convergence to O(1/ ...

2022

Mass transport of water vapor and ions from Å-scale graphene nanopores

Wan-Chi Lee

Hydrodynamics at the nanoscale involves both fundamental study and application of fluid and mass transport phenomena in nanometer-sized confinements. Nanopores in single-layer graphene can be highly attractive for exploring the molecular transport of gas a ...

EPFL2022

The thermally activated distortion with amplification effect and related variant selection in red gold alloys

Roland Logé, Cyril Cayron, Margaux Nathalie Dominique Larcher

Variant selection during the A1→L10 transformation in a polycrystalline red gold alloy close to equiatomic Au-Cu composition has been extensively studied by Electron Backscatter Diffraction (EBSD) in our previous work. The use of a mathematical description ...

2020

Centimeter-scale gas-sieving nanoporous single-layer graphene membrane

Kumar Varoon Agrawal, Mostapha Dakhchoune, Shiqi Huang, Guangwei He, Wan-Chi Lee

High-permeance, molecular-sieving, nanoporous single-layer graphene (NSLG) membranes are highly promising for gas separation. However, the formation of cracks during the transfer of NSLG to a low-cost porous support is difficult to avoid. These cracks are ...

2020

IMPACT: Interval-based Multi-pass Proteomic Alignment with Constant Traceback

James Richard Larus, Sahand Kashani, Stuart Anthony Byma

Darwin is a genomics co-processor that achieved a 15000x acceleration on long read assembly through innovative hardware and algorithm co-design. Darwins algorithms and hardware implementation were specifically designed for DNA analysis pipelines. This pape ...

2019

Electron backscatter diffraction study of variant selection during ordering phase transformation in L1(0)-type red gold alloy

Roland Logé, Cyril Cayron, Margaux Nathalie Dominique Larcher

A shape-memory effect is known to appear in red gold alloys with compositions close to Au-Cu. The aim of this paper is to study by electron backscatter diffraction (EBSD) the variant selection in the A1 -> L1(0) transformation occurring under stress, in be ...

INT UNION CRYSTALLOGRAPHY2019

Variant selection in martensitic steels

Annick Pauline Baur

The martensitic phase transformation in steel is one of the most famous solid state transformation because of its contribution in the development of the modern industry. This transformation from a face-centered cubic (FCC) high temperature phase, called th ...

EPFL2019

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