Related publications (87)

THE TWIN-ARGININE TRANSLOCATION PATHWAY IN THE OBLIGATE ANAEROBE DESULFITOBACTERIUM

Christof Holliger, Julien Maillard, Emmanuelle Rohrbach, Aurélie Duret

The genus Desulfitobacterium belong to the low-GC gram-positive phylogenic group and is a versatile obligate anaerobe capable of reducing very diverse terminal electron acceptors such as sulfite, nitrate, fumarate, thiosulfate, and a few polluting chlorina ...
2009

Cryoelectron microscopy structure of purified gamma-secretase at 12 A resolution

Lorène Aeschbach, Patrick Fraering, Hua Li

Gamma-secretase, an integral membrane protein complex, catalyzes the intramembrane cleavage of the beta-amyloid precursor protein (APP) during the neuronal production of the amyloid beta-peptide. As such, the protease has emerged as a key target for develo ...
Elsevier2009

On the Proton Transfer Mechanism in Ammonia-Bridged 7-Hydroxyquinoline: a First-Principles TDDFT Molecular Dynamics Study

Ursula Röthlisberger, Ivano Tavernelli

We have investigated the mechanism of proton transfer in the lowest photoexcited state of 7-hydroxyquinoline·(NH3)3 using TDDFT based molecular dynamics. We observe a concerted mechanism according to which all protons are transferred simultaneously in a fa ...
2009

Features of a twin-arginine signal peptide required for recognition by a Tat proofreading chaperone

Julien Maillard

The twin-arginine translocation (Tat) system is a bacterial protein targeting pathway. Tat-targeted proteins display signal peptides containing a distinctive SRRxFLK ‘twin-arginine’ motif. The Escherichia coli trimethylamine N-oxide reductase (TorA) bears ...
2008

Molecular and biochemical aspects of the chloroethene dehalorespiration process

Christof Holliger, Julien Maillard, Aurélie Duret, Laure Prat

Tetrachloroethene (PCE) is a major groundwater pollutant as a result of extensive use and spillage since 80 years. Several obligate anaerobic bacteria have the ability of using chlorinated aliphatic compounds as terminal electron acceptor in a process call ...
2008

Structural diversity in twin-arginine signal peptide-binding proteins

Julien Maillard

The twin-arginine transport (Tat) system is dedicated to the translocation of folded proteins across the bacterial cytoplasmic membrane. Proteins are targeted to the Tat system by signal peptides containing a twin-arginine motif. In Escherichia coli, many ...
2007

The structure of the prokaryotic cyclic nucleotide-modulated potassium channel MIoK1 at 16 angstrom resolution

Henning Paul-Julius Stahlberg

The gating ring of cyclic nucleotide-modulated channels is proposed to be either a two-fold symmetric dimer of dinners or a four-fold symmetric tetramer based on high-resolution structure data of soluble cyclic nucleotide-binding domains and functional dat ...
Elsevier BV2007

Structure of cytochrome c6A, a novel dithio-cytochrome of Arabidopsis thaliana, and its reactivity with plastocyanin: implications for function

Cytochrome c6A is a unique dithio-cytochrome present in land plants and some green algae. Its sequence and occurrence in the thylakoid lumen suggest that it is derived from cytochrome c6, which functions in photosynthetic electron transfer between the cyto ...
Elsevier2006

Redox Targeting of Insulating Electrode Materials: A New Approach to High-Energy-Density Batteries

Michael Graetzel, Qian Wang, Shaik Mohammed Zakeeruddin

A compact energy‐storage system based on redox targeting is proposed, by which insulating LiFePO4 particles can be reversibly charged and discharged by redox shuttle molecules (S; see scheme) even in the absence of conducting additives. The energy density ...
2006

Application of bench-scale biocalorimetry to photoautotrophic cultures

Urs von Stockar

Bench-scale biocalorimetry (>=1 L) allows for the detn. of the metabolic heat flow during bioprocesses under complete control of all process conditions for extended periods of time. It can be combined with a no. of online and off-line measurement technique ...
2005

Graph Chatbot

Chat with Graph Search

Ask any question about EPFL courses, lectures, exercises, research, news, etc. or try the example questions below.

DISCLAIMER: The Graph Chatbot is not programmed to provide explicit or categorical answers to your questions. Rather, it transforms your questions into API requests that are distributed across the various IT services officially administered by EPFL. Its purpose is solely to collect and recommend relevant references to content that you can explore to help you answer your questions.