Concept

Venous thrombosis

Related publications (32)

Risk prediction of developing venous thrombosis in combined oral contraceptive users

Background Venous thromboembolism (VTE) is a complex multifactorial disease influenced by genetic and environmental risk factors. An example for the latter is the regular use of combined oral contraceptives (CC), which increases the risk to develop VTE by ...

2017

Determination of a shear rate threshold for thrombus formation in intracranial aneurysms

Orestis Pileas Malaspinas, Ricardo Alberto Corredor Jerez, Bastien Chopard

Particular intra-aneurysmal blood flow conditions, created naturally by the growth of an aneurysm or induced artificially by implantation of a flow diverter stent (FDS), can potentiate intra-aneurysmal thrombosis. The aim of this study was to identify hemo ...

2015

Hemodynamic transition driven by stent porosity in sidewall aneurysms

Mohamed Farhat, Pierre Bouillot

The healing process of intracranial aneurysms (IAs) treated with flow diverter stents (FDSs) depends on the IA flow modifications and on the epithelization process over the neck. In sidewall IA models with straight parent artery, two main hemodynamic regim ...

Elsevier2015

Living-Engineered Valves for Transcatheter Venous Valve Repair

Peter Modregger, Marco Stampanoni

Background: Chronic venous insufficiency (CVI) represents a major global health problem with increasing prevalence and morbidity. CVI is due to an incompetence of the venous valves, which causes venous reflux and distal venous hypertension. Several studies ...

2014

Mathematical and Numerical Modeling of Healthy and Unhealthy Cerebral Arterial Tissues

Paolo Tricerri

Over the last two decades, we have witnessed an increasing application of mathematical models and numerical simulations for the study of the cardiovascular system. Indeed, both tools provide an important contribution to the analysis of the functioning of t ...

EPFL2014

The Angiotensin-Converting Enzyme 2/Angiotensin-(1-7)/Mas receptor axis: A potential target for treating thrombotic diseases

Nikolaos Stergiopoulos, Danielle Gomes Passos Silva

Despite many therapeutic advances leading to increasingly effective drug treatments, thrombotic events (such as ischaemic stroke, pulmonary embolism, deep venous thrombosis and acute myocardial infarction) still represent a major worldwide cause of morbidi ...

Schattauer Gmbh-Verlag Medizin Naturwissenschaften2012

Portable Technologies for Self-Monitoring of Coagulation Time: A Review

Philippe Renaud, Lynda Metref

Anti-coagulation treatments are required for medical conditions that become more and more frequent with the ageing of the population in developed countries (atrial fibrillation, deep-venous thrombosis, heart prosthetic valves, etc.). These treatments gener ...

2012

Numerical Fluid-Structure Interaction Model for the Connection of Outflow Cannula of LVAD to the Aorta

Alfio Quarteroni, Simone Deparis, Jean Bonnemain, Ludwig Von Segesser

Purpose: Connecting outflow cannula of LVAD to the aorta is an underexplored issue but may have considerable impact. In fact the hemodynamic modifications due to implantation in this region can cause thromboembolic events. It is therefore important to unde ...

2011

Nanoparticle conjugation and pulmonary delivery enhance the protective efficacy of Ag85B and CpG against tuberculosis

John McKinney, Neeraj Dhar, Eleonora Simeoni, Jeffrey Alan Hubbell, Melody Swartz, Alexandre de Titta, Marie Ballester, Miriella Carmela Pasquier, Cyntia De Piano

Vaccines that drive robust T-cell immunity against Mycobacterium tuberculosis (Mtb) are needed both for prophylactic and therapeutic purposes. We have recently developed a synthetic vaccine delivery platform with Pluronic-stabilized polypropylene sulfide n ...

2011

Local hemodynamics and intimal hyperplasia at the venous side of a porcine arteriovenous shunt

Nikolaos Stergiopoulos

Venous anastomotic intimal hyperplasia (IH) observed in the arteriovenous shunt (AVS) has been associated with disturbed hemodynamics. This study aims to correlate hemodynamics with wall histology and wall mechanics by examining the flow field in AVS with ...

2010

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