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Locomotion requires coordinated motor activity throughout an animal@s body. In both vertebrates and invertebrates, chains of coupled central pattern generators (CPGs) are commonly evoked to explain local rhythmic behaviors. In C. elegans, we report that pr ...
Parkinson's disease is a neurodegenerative disorder characterized by the progressive loss of dopaminergic neurons in the substantia nigra. While sporadic in the majority of cases, PD-linked dominant mutations in the α-synuclein and LRRK-2 genes, and recess ...
An efficient transistor level implementation of a flexible, programmable Triangular Function (TF) that can be used as a Triangular Neighborhood Function (TNF) in ultra-low power, self-organizing maps (SOMs) realized as Application-Specific Integrated Circu ...
Parkinson's disease is a neurodegenerative disorder characterized by the progressive loss of dopaminergic neurons in the substantia nigra. While sporadic in the majority of cases. PD-linked dominant mutations in the a-synuclein and LRRK-2 genes, and recess ...
In the mammalian dentate gyrus (DG) neurogenesis continues throughout life. Accumulating evidence suggests a unique contribution of adult-generated neurons in DG synaptic plasticity and hippocampal-mediated learning and memory functions. However, the preci ...
Oscillatory patterns of activity in various frequency ranges are ubiquitously expressed in cortical circuits. While recent studies in humans emphasized rhythmic modulations of neuronal oscillations ("second-order" rhythms), their potential involvement in i ...
Spike synchronization is thought to have a constructive role for feature integration, attention, associative learning, and the formation of bidirectionally connected Hebbian cell assemblies. By contrast, theoretical studies on spike-timing-dependent plasti ...
alpha-Synuclein (alpha-syn) is a presynaptic protein present at most nerve terminals, but its function remains largely unknown. The familial forms of Parkinson's disease associated with multiplications of the alpha-syn gene locus indicate that overabundanc ...
The paper presents a new CMOS implementation of the initialization mechanism for Kohonen self-organizing neural networks. A proper selection of initial values of the weights of the neurons exhibits a significant impact on the quality of the learning proces ...
In classical models of vision, low level visual tasks are explained by low level neural mechanisms. For example, in crowding, perception of a target is impeded by nearby elements because, as it is argued, responses of neurons coding for nearby elements are ...
