Concept

Neurosurgery

Related publications (40)

In vitro Implementation of Photopolymerizable Hydrogels as a Potential Treatment of Intracranial Aneurysms

Dominique Pioletti, Christophe Moser, Andreas Schmocker, Oriane Poupart

Intracranial aneurysms are increasingly being treated with endovascular therapy, namely coil embolization. Despite being minimally invasive, partial occlusion and recurrence are more frequent compared to open surgical clipping. Therefore, an alternative tr ...

FRONTIERS MEDIA SA2020

The combination of stereotactic radiosurgery with immune checkpoint inhibition or targeted therapy in melanoma patients with brain metastases: a retrospective study

Constantin Tuleasca, Krisztian Homicsko, Filipe Amândio Brandão Sanches Vong Martins, Olivier Michielin, Alexandre Wicky

Background Evidence pointing to a synergistic effect of stereotactic radiosurgery (SRS) with concurrent immunotherapy or targeted therapy in patients with melanoma brain metastases (BM) is increasing. We aimed to analyze the effect on overall survival (OS) ...

SPRINGER2020

Lausanne checklist for safe stereotactic radiosurgery

Constantin Tuleasca

Introduction Stereotactic radiosurgery (SRS) is increasingly used as a minimally invasive alternative in many neurosurgical conditions, including benign and malignant tumors, vascular malformations, and functional procedures. As for any surgical procedure, ...

2019

Comparison of MRI-based automated segmentation methods and functional neurosurgery targeting with direct visualization of the Ventro-intermediate thalamic nucleus at 7T

Jean-Philippe Thiran, Meritxell Bach Cuadra, Constantin Tuleasca, José Pedro Rebelo Ferreira Marques, Daniel Gallichan, João Pedro Forjaco Jorge, Elena Najdenovska

The ventro-intermediate nucleus (Vim), as part of the motor thalamic nuclei, is a commonly used target in functional stereotactic neurosurgery for treatment of drug-resistant tremor. As it cannot be directly visualized on routinely used magnetic resonance ...

2019

Pedicle screw navigation using surface digitization on the Microsoft HoloLens

Davide Scaramuzza, Jess Snedeker

Purpose In spinal fusion surgery, imprecise placement of pedicle screws can result in poor surgical outcome or may seriously harm a patient. Patient-specific instruments and optical systems have been proposed for improving precision through surgical naviga ...

2019

Non-invasive, Brain-controlled Functional Electrical Stimulation for Locomotion Rehabilitation in Individuals with Paraplegia

Mohamed Bouri, Solaiman Shokur, Miguel Nicolelis

Spinal cord injury (SCI) impairs the flow of sensory and motor signals between the brain and the areas of the body located below the lesion level. Here, we describe a neurorehabilitation setup combining several approaches that were shown to have a positive ...

2019

Virtual reality add-on device for stereotactic neurosurgery

Olaf Blanke, Bruno Herbelin, Philippe Passeraub

An add-on device for use in combination with a stereotactic apparatus is herein disclosed, the device including a stereotactic adapter, an optical support comprising lenses and a display support adapted to accommodate a virtual reality display. The stereot ...

2019

Brain-spine interface technologies to alleviate gait deficits after Parkinson's disease

Flavio Raschella

Gait and balance deficits are motor disabilities that typically develop late in the progression of Parkinson's disease (PD). These deficits are thought to be the result of dysregulated neural activity in the cortico-basal ganglia-thalamic-cortical motor lo ...

EPFL2019

Bioresorbable Endovascular Neural Interface for Minimally Invasive Neural Stimulation and Recording

Diego Ghezzi, Laura Ferlauto, Adele Fanelli

Recording and stimulation of brain circuits have been widely used to treat neurological disorders, such as epilepsy1 and Parkinson’s disease2. Current available techniques in this field commonly require invasive surgery potentially entailing both transient ...

2018

The Changing Paradigm for the Surgical Treatment of Large Vestibular Schwannomas

Constantin Tuleasca

Objective Planned subtotal resection followed by Gamma Knife surgery (GKS) in patients with large vestibular schwannoma (VS) has emerged during the past decade, with the aim of a better functional outcome for facial and cochlear function. Methods We prospe ...

2018

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