Publications related to Nuclear pore

Protocols for Subtomogram Averaging of Membrane Proteins in the Dynamo Software Package

Cryo-electron tomography allows low-resolution three-dimensional (3D) viewing of cellular organelles and macromolecular complexes present as multiple copies within a tomogram. These structures are computationally extracted and averaged in order to obtain h ...

Frontiers Media SA2018

Properties of LINE-1 proteins and repeat element expression in the context of amyotrophic lateral sclerosis

Didier Trono, Priscilla Turelli, Evaristo Jose Planet Letschert

BackgroundAmyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease involving loss of motor neurons and having no known cure and uncertain etiology. Several studies have drawn connections between altered retrotransposon expression and ALS. C ...

2018

An iris diaphragm mechanism to gate a cyclic nucleotide-gated ion channel

Henning Paul-Julius Stahlberg

Cyclic nucleotide-gated (CNG) ion channels are non-selective cation channels key to signal transduction. The free energy difference of cyclic-nucleotide (cAMP/cGMP) binding/unbinding is translated into mechanical work to modulate the open/closed probabilit ...

Springer Science and Business Media LLC2018

Nuclear Proteomics Uncovers Diurnal Regulatory Landscapes in Mouse Liver

Felix Naef, Loïc Dayon, Frédéric Bruno Martin Gachon, Martin Kussmann, Daniel Alain Dominique Marie Mauvoisin, Jingkui Wang, Florian Atger, Federico Sizzano

Diurnal oscillations of gene expression controlled by the circadian clock and its connected feeding rhythm enable organisms to coordinate their physiologies with daily environmental cycles. While available techniques yielded crucial insights into regulatio ...

Elsevier2017

Computer simulations reveal mechanisms that organize nuclear dynein forces to separate centrosomes

Pierre Gönczy, Alessandro De Simone

Centrosome separation along the surface of the nucleus at the onset of mitosis is critical for bipolar spindle assembly. Dynein anchored on the nuclear envelope is known to be important for centrosome separation, but it is unclear how nuclear dynein forces ...

Amer Soc Cell Biology2017

Damage of eukaryotic cells by the pore-forming toxin sticholysin II: Consequences of the potassium efflux

Françoise Gisou van der Goot Grunberg, Sylvia Ho

Pore-forming toxins (PFTs) form holes in membranes causing one of the most catastrophic damages to a target cell. Target organisms have evolved a regulated response against PFTs damage including cell membrane repair. This ability of cells strongly depends ...

Elsevier Science Bv2017

Regulated intramembrane proteolysis of the AXL receptor kinase generates an intracellular domain that localizes in the nucleus of cancer cells

Patrick Fraering

Deregulation of the TAM (TYRO3, AXL, and MERTK) family of receptor tyrosine kinases (RTKs) has recently been demonstrated to predominately promote survival and chemoresistance of cancer cells. Intramembrane proteolysis mediated by presenilin/gamma-secretas ...

Federation Amer Soc Exp Biol2017

Computational development of the nanoporous materials genome

Berend Smit, Peter George Boyd, Yongjin Lee

There is currently a push towards big data and data mining in materials research to accelerate discovery. Zeolites, metal-organic frameworks and other related crystalline porous materials are not immune to this phenomenon, as evidenced by the proliferation ...

Nature Publishing Group2017

Identification of Chlamydomonas Central Core Centriolar Proteins Reveals a Role for Human WDR90 in Ciliogenesis

Pierre Gönczy, Romain Hamelin, Florence Armand, Coralie Busso, Paul Guichard, Virginie Hamel, Isabelle Fluckiger

Centrioles are evolutionarily conserved macromolecular structures that are fundamental to form cilia, flagella, and centrosomes. Centrioles are 9-fold symmetrical microtubule-based cylindrical barrels comprising three regions that can be clearly distinguis ...

2017

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Nuclear pore

Protocols for Subtomogram Averaging of Membrane Proteins in the Dynamo Software Package

Properties of LINE-1 proteins and repeat element expression in the context of amyotrophic lateral sclerosis

An iris diaphragm mechanism to gate a cyclic nucleotide-gated ion channel

Osmotic power generator

Nuclear Proteomics Uncovers Diurnal Regulatory Landscapes in Mouse Liver

Computer simulations reveal mechanisms that organize nuclear dynein forces to separate centrosomes

Damage of eukaryotic cells by the pore-forming toxin sticholysin II: Consequences of the potassium efflux

Regulated intramembrane proteolysis of the AXL receptor kinase generates an intracellular domain that localizes in the nucleus of cancer cells

Computational development of the nanoporous materials genome

Identification of Chlamydomonas Central Core Centriolar Proteins Reveals a Role for Human WDR90 in Ciliogenesis

Graph Chatbot

Chat with Graph Search

Regulated intramembrane proteolysis of the AXL receptor kinase generates an intracellular domain that localizes in the nucleus of cancer cells

Computer simulations reveal mechanisms that organize nuclear dynein forces to separate centrosomes

Nuclear Proteomics Uncovers Diurnal Regulatory Landscapes in Mouse Liver

Osmotic power generator

An iris diaphragm mechanism to gate a cyclic nucleotide-gated ion channel

Computational development of the nanoporous materials genome

Damage of eukaryotic cells by the pore-forming toxin sticholysin II: Consequences of the potassium efflux

Properties of LINE-1 proteins and repeat element expression in the context of amyotrophic lateral sclerosis

Protocols for Subtomogram Averaging of Membrane Proteins in the Dynamo Software Package

Identification of Chlamydomonas Central Core Centriolar Proteins Reveals a Role for Human WDR90 in Ciliogenesis