Concept

Minimally conscious state

Related publications (35)

Beyond Quiescent and Active: Intermediate Microglial Transcriptomic States in a Mouse Model of Down Syndrome

Research on microglia in Down syndrome (DS) has shown that microglial activation, increased inflammatory gene expression, and oxidative stress occur at different ages in DS brains. However, most studies resulted in simplistic definitions of microglia as qu ...

Basel2024

Transient brain activity dynamics discriminate levels of consciousness during anesthesia

Dimitri Nestor Alice Van De Ville, Elvira Pirondini, Ayberk Ozkirli

The awake mammalian brain is functionally organized in terms of large-scale distributed networks that are constantly interacting. Loss of consciousness might disrupt this temporal organization leaving patients unresponsive. We hypothesize that characterizi ...

Nature Portfolio2024

Cortical and subcortical changes in resting-state neuronal activity and connectivity in early symptomatic ALS and advanced frontotemporal dementia

Alessandra Griffa

The objective of this study was to examine if patterns of resting-state brain activity and functional connectivity in cortical and subcortical regions in patients with early symptomatic amyotrophic lateral sclerosis (ALS) resemble those of behavioural vari ...

ELSEVIER SCI LTD2022

Probabilistic Symbol Sequence Matching and its Application to Pathological Speech Intelligibility Assessment

Julian David Fritsch

Matching of a test signal to a reference word hypothesis forms the core of many speech processing problems, including objective speech intelligibility assessment. This paper first shows that the comparison of two speech signals can be formulated as matchin ...

Idiap2021

Structural control energy of resting-state functional brain states reveals less cost-effective brain dynamics in psychosis vulnerability

Dimitri Nestor Alice Van De Ville, Marie Schaer

How the brain's white-matter anatomy constrains brain activity is an open question that might give insights into the mechanisms that underlie mental disorders such as schizophrenia. Chromosome 22q11.2 deletion syndrome (22q11DS) is a neurodevelopmental dis ...

WILEY2021

Resting-State Brain Activity for Early Prediction Outcome in Postanoxic Patients in a Coma with Indeterminate Clinical Prognosis

Dimitri Nestor Alice Van De Ville

The authors used resting-state fMRI in a prospective study to compare whole-brain functional connectivity between patients with good and poor outcomes, implementing support vector machine learning. They automatically predicted coma outcome using resting-st ...

AMER SOC NEURORADIOLOGY2020

Automatic Pathological Speech Intelligibility Assessment Exploiting Subspace-Based Analyses

Hervé Bourlard, Ina Kodrasi, Parvaneh Janbakhshi

Competitive state-of-the-art automatic pathological speech intelligibility measures typically rely on regression training on a large number of features, require a large amount of healthy speech training data, or are applicable only to phonetically balanced ...

IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC2020

Spectral Subspace Analysis for Automatic Assessment of Pathological Speech Intelligibility

Hervé Bourlard, Ina Kodrasi, Parvaneh Janbakhshi

Speech intelligibility is an important assessment criterion of the communicative performance of pathological speakers. To assist clinicians in their assessment, time- and cost-efficient automatic intelligibility measures offering a repeatable and reliable ...

2019

Multisensory perceptual awareness: Categorical or graded?

Olaf Blanke, Nathan Quentin Faivre, Jean-Paul Noel

Neural evidence suggests that mechanisms associated with conscious access (i.e., the ability to report on a conscious state) are “all-or-none”. Upon crossing some threshold, neural signals are globally broadcast throughout the brain and allow conscious rep ...

2019

PATHOLOGICAL SPEECH INTELLIGIBILITY ASSESSMENT BASED ON THE SHORT-TIME OBJECTIVE INTELLIGIBILITY MEASURE

Hervé Bourlard, Ina Kodrasi, Parvaneh Janbakhshi

Impaired speech intelligibility in motor speech disorders arising due to neurological diseases negatively affects the communication ability and quality of life of patients. Reliable and cost-effective measures to automatically assess speec ...

2019

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