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Amyloid plaques

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Amyloid plaques

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Amyloid ß-derived switch-peptides as tool to study conformational changes relevant in degenerative diseases

Rapid purification of active gamma-secretase, an intramembrane protease implicated in Alzheimer's disease

Apomorphine inhibitors of amyloid-beta (abeta) fibril formation and their use in amyloidosis based disease

Switch-peptides: design and characterization of controllable super-amyloid-forming host-guest peptides as tools for identifying anti-amyloid agents

Hsp104 targets multiple intermediates on the amyloid pathway and suppresses the seeding capacity of Abeta fibrils and protofibrils

The ratio of monomeric to aggregated forms of Abeta40 and Abeta42 is an important determinant of amyloid-beta aggregation, fibrillogenesis, and toxicity

Induction of tau pathology by intracerebral infusion of amyloid-beta-containing brain extract and by amyloid-beta deposition in APP x tau transgenic mice

Disruption of amyloid-derived peptide assemblies through the controlled induction of a beta-sheet to alpha-helix transformation: application of the switch concept

Structural and Functional Determinants of gamma-Secretase, an Intramembrane Protease Implicated in Alzheimer's Disease

Switch-peptides as folding precursors in self-assembling peptides and amyloid fibrillogenesis