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Protein kinases are key regulators of many biochemical processes in eukaryotic cells. Malaria parasites, in spite of all their peculiarities, are not likely to represent an exception in this respect. Over the past few years, several genes encoding Plasmodi ...
Research into cell cycle control in protozoan parasites, which are responsible for major public health problems in the developing world, has been hampered by the difficulties in performing classical genetic analysis with these organisms. Nevertheless, in a ...
The central reaction in the process of N-linked protein glycosylation in eukaryotic cells, the transfer of the oligosaccharide Glc(3)Man(9)GlcNAc(2) from the lipid dolicholpyrophosphate to selected asparagine residues, is catalyzed by the oligosaccharyltra ...
The minimal photounit of the photosynthetic membranes of the purple non-sulfur bacterium Rhodospirillum rubrum, comprising the reaction center and the light-harvesting complex has been purified and crystd. in two dimensions in the presence of added phospho ...
An extensive random mutagenesis study on the function of nine residues in the subunit binding site of FimC was conducted to evaluate the mol. mechanisms of subunit binding by FimC and the contribution of chaperone surface residues. Five plasmid libraries o ...
Deutsche Akademie der Naturforscher Leopoldina2001
Melanin pigments are found in all biological kingdoms. At the cellular level, correct pigmentation depends not only on correct migration of pigment cells (melanocytes) and their precursors (melanoblasts), but also on specialized cytoplasmic organelles, mel ...
A variety of extracellular ligands and pathogens interact with raft domains in the plasma membrane of eukaryotic cells. In this study, we examined the role of lipid rafts and raft-associated glycosylphosphatidylinositol (GPI)-anchored proteins in the proce ...
We have purified authentic CLIP-170 (cytoplasmic linker protein of 170 kDa) and fragments comprising functional domains of the protein to characterize the structural basis of the function of CLIP-170. Analysis of authentic CLIP-170 and the recombinant frag ...
A unique solar cell fabrication procedure has been developed using natural anthocyanin dyes extracted from berries. It can be reproduced with a minimum amount of resources in order to provide an interdisciplinary approach for lower-division undergraduate s ...
Brucella abortus is an intracellular pathogen that replicates within a membrane-bounded compartment. In this study, we have examined the intracellular pathway of the virulent B. abortus strain 2308 (S2308) and the attenuated strain 19 (S19) in HeLa cells. ...
