Concept

Do-it-yourself biology

Summary
Do-it-yourself biology (DIY biology, DIY bio) is a biotechnological social movement in which individuals, communities, and small organizations study biology and life science using the same methods as traditional research institutions. DIY biology is primarily undertaken by individuals with limited research training from academia or corporations, who then mentor and oversee other DIY biologists with little or no formal training. This may be done as a hobby, as a not-for-profit endeavor for community learning and open-science innovation, or for profit, to start a business. Other terms are also associated with the do-it-yourself biology community. The terms biohacking and wetware hacking emphasize the connection to hacker culture and the hacker ethic. The term hacker is used in the original sense of finding new and clever ways to do things. The term biohacking is also used by the grinder body modification community, which is considered related but distinct from the do-it-yourself biology movement. The term biopunk emphasizes the techno-progressive, political, and artistic elements of the movement. The term "biohacking" as well as the concept of do-it-yourself biology has been known as early as 1988. Biohacking entered the San Francisco programmer and maker communities as early as 2005, through simple demonstrations of basic experiments. As DIYbio experiments became the focus of SuperHappyDevHouse hackers, the hobby gained additional momentum. In 2005 Rob Carlson wrote in an article in Wired: "The era of garage biology is upon us. Want to participate? Take a moment to buy yourself a lab on eBay." He then set up a garage lab the same year, working on a project he had previously worked at the Molecular Sciences Institute in Berkeley, California. In 2008, the DIYbio organization was founded by Jason Bobe and Mackenzie Cowell and its first meeting held. In 2010, Genspace opened the first community biology lab, Ten months later it was followed by BioCurious, and Victoria Makerspace.
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Genome editing
Genome editing, or genome engineering, or gene editing, is a type of genetic engineering in which DNA is inserted, deleted, modified or replaced in the genome of a living organism. Unlike early genetic engineering techniques that randomly inserts genetic material into a host genome, genome editing targets the insertions to site-specific locations.