A bezoar (ˈbizɔ:r ) is a mass often found trapped in the gastrointestinal system, though it can occur in other locations. A pseudobezoar is an indigestible object introduced intentionally into the digestive system. There are several varieties of bezoar, some of which have inorganic constituents and others organic. The term has both modern (medical, scientific) and traditional usage. Food boluses (or boli; singular bolus) have the archaic and positive meaning of bezoar, and are composed of loose aggregates of food items such as seeds, fruit pith, or pits, as well as other types of items such as shellac, bubble gum, soil, and concretions of some medications. Lactobezoars are a specific type of food bezoar comprising inspissated milk. It is most commonly seen in premature infants receiving formula foods. Pharmacobezoars (or medication bezoars) are mostly tablets or semiliquid masses of drugs, normally found following an overdose of sustained-release medications. Phytobezoars are composed of indigestible plant material (e.g., cellulose), and are frequently reported in patients with impaired digestion and decreased gastric motility. Diospyrobezoar is a type of phytobezoar formed from unripe persimmons. Coca-Cola has been used to treat them. Trichobezoar is a bezoar formed from hair – an extreme form of hairball. Humans who frequently consume hair sometimes require these to be removed. In cases of Rapunzel syndrome, surgery may be required. A bezoar in the esophagus is common in young children and in horses; in horses, it is known as choke. A bezoar in the large intestine is known as a fecalith. A bezoar in the trachea is called a tracheobezoar. Esophageal bezoars discovered in nasogastrically fed patients on mechanical ventilation and sedation are reported to be due to the precipitation of certain food types rich in casein, which are precipitated with gastric acid reflux to form esophageal bezoars. Bezoars can also be caused by gastroparesis due to the slowing of gastric emptying, which allows food to form a bolus.