Concept
Pinworm infection
Related publications (32)
Dynamic persistence of UPEC intracellular bacterial communities in a human bladder-chip model of urinary tract infection
John McKinney, Neeraj Dhar, Vivek Vijay Thacker, François Signorino-Gelo, Kunal Sharma, Thomas Marie Simonet
Uropathogenic Escherichia coli (UPEC) proliferate within superficial bladder umbrella cells to form intracellular bacterial communities (IBCs) during early stages of urinary tract infections. However, the dynamic responses of IBCs to host stresses and anti ...
2021Immune serum-activated human macrophages coordinate with eosinophils to immobilize Ascaris suum larvae
Beatrice Volpe, Julia Esser-von Bieren, Tiffany Babette Angélique Bouchery, Kathleen Shah
Helminth infection represents a major health problem causing approximately 5 million disability-adjusted life years worldwide. Concerns that repeated anti-helminthic treatment may lead to drug resistance render it important that vaccines are developed but ...
WILEY2020Gene drives for schistosomiasis transmission control
Schistosomiasis is one of the most important and widespread neglected tropical diseases (NTD), with over 200 million people infected in more than 70 countries; the disease has nearly 800 million people at risk in endemic areas. Although mass drug administr ...
2019Automated Platform for Long-Term Culture and High-Content Phenotyping of Single C. elegans Worms
Johan Auwerx, Martinus Gijs, Matteo Cornaglia, Laurent Mouchiroud, Elena Katsyuba, Hüseyin Baris Atakan, Rongrong Xiang
The nematode Caenorhabditis elegans is a suitable model organism in drug screening. Traditionally worms are grown on agar plates, posing many challenges for long-term culture and phenotyping of animals under identical conditions. Microfluidics allows for ' ...
2019House dust mite drives proinflammatory eicosanoid reprogramming and macrophage effector functions
Nicola Harris, Julia Esser-von Bieren, Tiffany Babette Angélique Bouchery
Background Eicosanoid lipid mediators play key roles in type 2 immune responses, for example in allergy and asthma. Macrophages represent major producers of eicosanoids and they are key effector cells of type 2 immunity. We aimed to comprehensively track e ...
WILEY2019IL-4R alpha-Expressing B Cells Are Required for CXCL13 Production by Fibroblastic Reticular Cells
Nicola Harris, Lalit Kumar Dubey
Adaptive type 2 immune responses against the intestinal helminth Heligmosomoides polygyrus (Hp) require the interaction of follicle-associated CXCR5(+) dendritic cells with naive T cells in the draining mesenteric lymph nodes (mLNs). However, the source of ...
CELL PRESS2019Empirical Characterization of Particle Size Distribution Spatial Dynamics for Helminth Eggs Detection in Waste Stabilization Ponds (WSP)
This study assesses seasonal particle size distribution (PSD) dynamics inside a waste stabilization ponds (WSP) (Buguruni, Tanzania) to understand settling dynamics of wastewater particles with an interest in helminth eggs. Results indicate that particles ...
2018Intestinal helminths modulate the gut microbiome
Intestinal parasitic worms (commonly named intestinal helminths) affect close to one quarter of the world population and cause major losses for the livestock industry. These parasites establish chronic infections by modulation the immunity of their host. T ...
EPFL2018Risk Perception and Epidemics in Complex Computer Networks
We present a self-organised method for quickly obtaining the epidemic threshold of infective processes on networks. Starting from simple percolation models, we introduce the possibility that the effective infection probability is affected by the perception ...
IEEE2018