Publications related to Oxidative phosphorylation

New tool for studying the biosynthetic role of glucose in brain at the nanometer scale

Anders Meibom, Graham Knott, Stéphane Laurent Escrig, Arnaud Comment, Yuhei Takado, Mojgan Masoodi

Background: The brain consumes a considerable amount of glucose relative to its size. Brain glucose is a source of energy, mainly via oxidative phosphorylation, as well as a source of building blocks for synthesising macromolecules. Little is known about t ...

2014

A New Role for Escherichia coli DsbC Protein in Protection against Oxidative Stress

Camille Véronique Bernadette Goemans

We report a new function for Escherichia coli DsbC, a protein best known for disulfide bond isomerization in the periplasm. We found that DsbC regulates the redox state of the single cysteine of the l-arabinose-binding protein AraF. This cysteine, which ca ...

2014

Characterisation of intracellular metabolic states in cells presenting the Warburg phenotype

Vassily Hatzimanikatis, Joana Raquel Pinto Vieira

Cancer cells have been shown to undergo a metabolic reprogramming, known as the Warburg effect, which results in enhanced glycolytic fluxes and down- regulated oxidative phosphorylation even in the presence of abundant oxygen. Experiments show that disrupt ...

2014

Toward Quantitative Measurements of Enzyme Kinetics by Dissolution Dynamic Nuclear Polarization

Geoffrey Bodenhausen, Aurélien Bornet, Sami Jannin, Jonas Milani, Daniel Abergel

Dissolution dynamic nuclear polarization (D-DNP) experiments enabled us to study the kinetics of the enzymatic phosphorylation reaction of glucose to form glucose-6-phosphate (G6P) by hexokinase (HK), with or without the presence of an excess of G6P, which ...

2014

Functional diversity of reductive dehalogenases in a bacterial consortium degrading chloroethenes

Christof Holliger, Julien Maillard, Géraldine Florence Buttet, Sébastien Keller

Chlorinated hydrocarbon pollution threatens nature and human health due to its toxic and carcinogenic potential. Enrichment cultures were investigated for the bioremediation potential of tetrachloroethene (PCE). This process is based on bacterial anaerobic ...

2014

Hyperpolarized 13C lactate as a substrate for in vivo metabolic studies in skeletal muscle

Rolf Gruetter, Arnaud Comment, Josefina Adriana Maria Bastiaansen, Hikari Ananda Infinity Yoshihara, Yuhei Takado

Resting skeletal muscle has a preference for the oxidation of lipids compared to carbohydrates and a shift towards carbohydrate oxidation is observed with increasing exercise. Lactate is not only an end product in skeletal muscle but also an important meta ...

2014

Effective treatment of mitochondrial myopathy by nicotinamide riboside, a vitamin B3

Johan Auwerx, Eija Riitta Pirinen

Nutrient availability is the major regulator of life and reproduction, and a complex cellular signaling network has evolved to adapt organisms to fasting. These sensor pathways monitor cellular energy metabolism, especially mitochondrial ATP production and ...

Wiley Open Access2014

Delayed bactericidal response of Mycobacterium tuberculosis to bedaquiline involves remodelling of bacterial metabolism

John McKinney, Neeraj Dhar, Muhittin Emre Özdemir, Ping Lu

Bedaquiline (BDQ), an ATP synthase inhibitor, is the first drug to be approved for treatment of multidrug-resistant tuberculosis in decades. Though BDQ has shown excellent efficacy in clinical trials, its early bactericidal activity during the first week o ...

Nature Publishing Group2014

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Oxidative phosphorylation

New tool for studying the biosynthetic role of glucose in brain at the nanometer scale

A New Role for Escherichia coli DsbC Protein in Protection against Oxidative Stress

Do crosstalks with primary and secondary metabolism limit or stimulate the detoxification of xenobiotics?

Characterisation of intracellular metabolic states in cells presenting the Warburg phenotype

Toward Quantitative Measurements of Enzyme Kinetics by Dissolution Dynamic Nuclear Polarization

Fast Proton Exchange in Histidine: Measurement of Rate Constants through Indirect Detection by NMR Spectroscopy

Functional diversity of reductive dehalogenases in a bacterial consortium degrading chloroethenes

Hyperpolarized 13C lactate as a substrate for in vivo metabolic studies in skeletal muscle

Effective treatment of mitochondrial myopathy by nicotinamide riboside, a vitamin B3

Delayed bactericidal response of Mycobacterium tuberculosis to bedaquiline involves remodelling of bacterial metabolism

Graph Chatbot

Chat with Graph Search

Characterisation of intracellular metabolic states in cells presenting the Warburg phenotype

A New Role for Escherichia coli DsbC Protein in Protection against Oxidative Stress

New tool for studying the biosynthetic role of glucose in brain at the nanometer scale

Do crosstalks with primary and secondary metabolism limit or stimulate the detoxification of xenobiotics?

Toward Quantitative Measurements of Enzyme Kinetics by Dissolution Dynamic Nuclear Polarization

Fast Proton Exchange in Histidine: Measurement of Rate Constants through Indirect Detection by NMR Spectroscopy

Effective treatment of mitochondrial myopathy by nicotinamide riboside, a vitamin B3

Delayed bactericidal response of Mycobacterium tuberculosis to bedaquiline involves remodelling of bacterial metabolism

Functional diversity of reductive dehalogenases in a bacterial consortium degrading chloroethenes

Hyperpolarized 13C lactate as a substrate for in vivo metabolic studies in skeletal muscle