Concept

Motor system

Related publications (116)

Mesenchymal stem cells restore cortical rewiring after neonatal ischemia in mice

Objective: A study was undertaken to investigate the effect of neonatal hypoxic-ischemic (HI) brain damage and mesenchymal stem cell (MSC) treatment on the structure and contralesional connectivity of motor function-related cerebral areas. Methods: Brain r ...

Wiley-Blackwell2012

High-performance and site-directed in utero electroporation by a triple-electrode probe

Diego Ghezzi

From its introduction, in utero electroporation has arisen as a powerful tool to manipulate neural-precursor cells of the parietal cortex and their progeny in vivo. Although this technique has unlimited potentials for targeting numerous brain areas, the ex ...

2012

Assessing the integrity of corticospinal pathways from primary and secondary cortical motor areas after stroke

Friedhelm Christoph Hummel, Chang-Hyun Park

Aside from the primary motor cortex, the corticospinal tract (CST) also receives fibers from dorsal and ventral premotor cortices and supplementary motor area, all of which might potentially contribute to motor function after stroke. We sought to quantify ...

2012

Stump nerve signals during transcranial magnetic motor cortex stimulation recorded in an amputee via longitudinal intrafascicular electrodes

Silvestro Micera, Jacopo Rigosa

Do central and peripheral motor pathways associated with an amputated limb retain at least some functions over periods of years? This problem could be addressed by evaluating the response patterns of nerve signals from peripheral motor fibers during transc ...

2011

Lentiviral vectors express chondroitinase ABC in cortical projections and promote sprouting of injured corticospinal axons

Bernard Schneider, Jean-Charles Bensadoun

Several diseases and injuries of the central nervous system could potentially be treated by delivery of an enzyme, which might most effectively be achieved by gene therapy. In particular, the bacterial enzyme chondroitinase ABC is beneficial in animal mode ...

Elsevier2011

Characterisation of Living Matter Using Advanced Spectroscopy Techniques

Markus Bonda

In the context of an ageing society neurodegenerative disease have become more and more frequent among humans. Opposing the benefits of a longer life, these diseases have thus triggered research on neurons and how they interact with each other. In vitro as ...

EPFL2011

Joint action modulates motor system involvement during action observation in 3-year-olds

Michiel van Elk

When we are engaged in a joint action, we need to integrate our partner's actions with our own actions. Previous research has shown that in adults the involvement of one's own motor system is enhanced during observation of an action partner as compared to ...

2011

Redundant information encoding in primary motor cortex during motor tasks

Michael Christoph Gastpar

Information encoded in neuron ensembles has previously been hypothesized to be highly redundant, despite the apparent inefficiency of a redundant encoding system. The recent availability of intracortical, multi-electrode recordings has enabled the possibil ...

IEEE2011

Synchrotron Infrared Microspectroscopy Detecting the Evolution of Huntington's Disease Neuropathology and Suggesting Unique Correlates of Dysfunction in White versus Gray Brain Matter

László Forró, Sylvia Jeney, Heike Runne, Markus Bonda

Huntington's disease (HD), caused by a mutation of the corresponding gene encoding the protein huntingtin (htt), is characterized by progressive deterioration of cognitive and motor functions, paralleled by extensive loss of striatal neurons. At the cellul ...

2011

Learning to use novel objects: A training study on the acquisition of novel action representations

Michiel van Elk, Christian Pfeiffer

Many studies have suggested that the motor system is organized in a hierarchical fashion, around the prototypical end location associated with using objects. However, most studies supporting the hierarchical view have used well-known actions and objects th ...

2011

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