Concept
Paralysis
Related publications (34)
Brain-controlled spinal cord stimulation to restore mobility after spinal cord injury.
Spinal Cord Injury (SCI) affects almost 500,000 people every year, causing complete paralysis of both legs in severe cases, with no current treatment perspective. However, new neuroengineering technologies, such as the Brain Spine Interface (BSI), have eme ...
EPFL2023Modelisation of fiber reinforced DEAs
The aim of this "Face Reconstruction" project is to enable people with paralysis in one half of their face to recover facial expressions. To do this, we’ll replace the paralyzed muscle with an DEA which we’ll connect to the nerve on the other side of the f ...
2023Puppeteer and Marionette: Learning Anticipatory Quadrupedal Locomotion Based on Interactions of a Central Pattern Generator and Supraspinal Drive
Auke Ijspeert, Guillaume Denis Antoine Bellegarda, Milad Shafiee Ashtiani
Quadruped animal locomotion emerges from the interactions between the spinal central pattern generator (CPG), sensory feedback, and supraspinal drive signals from the brain. Computational models of CPGs have been widely used for investigating the spinal co ...
New York2023Sensor-based control strategies for integration of epidural electrical stimulation in rehabilitation after spinal cord injury
Spinal Cord Injury (SCI) results in damage to neural circuitry connecting the brain to the periphery. Consequently, sensory and motor function is lost, to varying degree, depending on the site and severity of the lesion. More than half of spinal cord injur ...
EPFL2022Natural and targeted circuit reorganization after spinal cord injury
Grégoire Courtine, Jocelyne Bloch, Quentin Barraud, Jordan Squair, Mark Andrew Anderson, Claudia Kathe, Matthieu Pierre Gautier, Thomas Haynes Hutson
The authors summarize changes in circuits after spinal cord injury and current strategies to target these circuits in order to improve recovery, but also advocate for new concepts of reorganizing circuits informed by multi-omic single-cell atlases. A spina ...
NATURE PORTFOLIO2022Learning to control a BMI-driven wheelchair for people with severe tetraplegia
José del Rocio Millán Ruiz, Kyuhwa Lee, Serafeim Perdikis, Luca Tonin, Bastien Orset
Mind-controlled wheelchairs are an intriguing assistive mobility solution applicable in complete paralysis. Despite progress in brain-machine interface (BMI) technology, its translation remains elusive. The primary objective of this study is to probe the h ...
Cambridge2022Fabrication of a planar Dielectric Elastomer Actuator and Characterization of its self-discharge rate
Facial paralysis is a very challenging condition that can affect all age groups. It impacts facial movement, appearance, emotional expression, social interactions, and critical functions such as smiling, eating, speaking, or blinking. There are a wide vari ...
2022Development of a peripheral neuroprosthesis to elicit fine hand movements in primates
Marion Aimée Geneviève Badi-Dubois
Neurological disorders such as spinal cord lesion and stroke disturb sensorimotor pathways and result in severe motor deficits that can dreadfully impact the quality of life of affected individuals. Strategies aiming at restoring hand function after upper- ...
EPFL2021Corticolumbar dynamics during recovery after spinal cord injury
In humans, a severe spinal cord contusion interrupts the vast majority of supraspinal projections to the spinal cord below the lesion. Permanent paralysis results from the chronic failure of these spared projections to engage lumbar circuits producing leg ...
EPFL2020Spatiotemporal stimulation strategies in neuroprostheses to improve locomotion after spinal cord injury
Spinal cord injury (SCI) disrupts communication within central nervous system and lead to range of neurological disorders including paralysis. Current rehabilitation strategies to restore locomotion are poorly effective in people with severe SCI. Epidural ...
EPFL2019