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Clinical observations have shown that GABA-acting benzodiazepines exert paradoxical excitatory effects in autism, suggesting elevated intracellular chloride (Cl-)(i) and excitatory action of GABA. In a previous double-blind randomized study, we have shown ...
The thalamus transmits sensory information to the neocortex and receives neocortical, subcortical, and neuromodulatory inputs. Despite its obvious importance, surprisingly little is known about thalamic function in awake animals. Here, using intracellular ...
Hybrid interfaces between organic semiconductors and living tissues represent a new tool for in-vitro and in-vivo applications, bearing a huge potential, from basic researches to clinical applications. In particular, light sensitive conjugated polymers can ...
Nerve cells in the brain generate sequences of action potentials with a complex statistics. Theoretical attempts to understand this statistics were largely limited to the case of a temporally uncorrelated input (Poissonian shot noise) from the neurons in t ...
The calculation of the steady-state probability density for multidimensional stochastic systems that do not obey detailed balance is a difficult problem. Here we present the analytical derivation of the stationary joint and various marginal probability den ...
A 2R-cell with a 10 cm2 active area LSCF cathode on a CGO buffer layer was tested at 780°C under thermal and RedOx cycling conditions; 20 thermal cycles were performed between 780°C and 100°C, using 200°C/h heating ramps and natural cooling, followed by 20 ...
Handwritten characters in administrative antique documents from three centuries have been detected using different synchrotron X-ray imaging techniques. Heavy elements in ancient inks, present even for everyday administrative manuscripts as shown by X-ray ...
Intracellular recordings of membrane potential in vitro have defined fundamental properties of synaptic communication. Much less is known about the properties of synaptic connectivity and synaptic transmission in vivo. Here, we combined single-cell opto-ge ...
The motor systems of the mammalian brain are a remarkable product of many millions of years of evolution. It is the motor systems that make us and other mammals mobile, that guide our actions in response to sensory information and conversely modulate the v ...
The relationship between transmitter release evoked by action potentials and spontaneous release has fascinated neuroscientists for half a century, and separate biological roles for spontaneous release are emerging. Nevertheless, separate functions for spo ...
