Concept

Heart valve

Related publications (81)

Experimental study of atrial fibrillation cycle length during rapid atrial septal pacing

Jean-Marc Vesin, Adrian Luca, Sasan Yazdani

Computer model-based simulations have shown that rapid stimulation at 60-100% of atrial fibrillation cycle length (AFCL) from a ring of electrodes located around the septum may induce local capture in both atria for most AF dynamics. The present study aims ...

2017

Passive flow control valve for protein delivery

Philippe Renaud, Harald Van Lintel

Passive ow control valves are usually intended to deliver or drain a uid at a constant rate independently of pressure variations. Micro uidic devices made of a stack of two plates are considered here: the rst plate comprises a exible silicon membrane havin ...

2017

Endothelial Notch1 Is Required for Proper Development of the Semilunar Valves and Cardiac Outflow Tract

Freddy Radtke

Background-Congenital heart disease is the most common type of birth defect, affecting approximate to 2% of the population. Malformations involving the cardiac outflow tract and semilunar valves account for >50% of these cases predominantly because of a bi ...

Wiley-Blackwell2016

Numerical modeling of heart valves using resistive Eulerian surfaces

Alfio Quarteroni, Aymen Laadhari

The goal of this work is the development and numerical implementation of a mathematical model describing the functioning of heart valves. To couple the pulsatile blood flow with a highly deformable thin structure (the valve's leaflets), a resistive Euleria ...

Wiley-Blackwell2016

MATHICSE Technical Report : Integrated Heart – Coupling multiscale and multiphysics models for the simulation of the cardiac function

Alfio Quarteroni, Ricardo Esteban Ruiz Baier, Toni Mikael Lassila, Simone Rossi

Mathematical modelling of the human heart and its function can expand our understanding of various cardiac diseases, which remain the most common cause of death in the developed world. Like other physiological systems, the heart can be understood as a comp ...

MATHICSE2016

MATHICSE Technical Report : A patient-specific aortic valve model based on moving resistive immersed implicit surfaces

Alfio Quarteroni, Luca Dede', Elena Faggiano, Marco Fedele

In this paper, we propose a full computational pipeline to simulate the hemodynamics in the aorta including the valve. Closed and open valve surfaces, as well as the lumen aorta, are reconstructed directly from medical images using new ad hoc algorithms, a ...

MATHICSE2016

Atrial fibrillation septal pacing: translation of modelling results

Adrian Luca

Aims: Atrial fibrillation (AF) septal pacing consists of rapid pacing from a ring of electrodes around the atrial septum, leading to local capture of both atria during AF. The present model-based study evaluated the impact of the number of stimulation elec ...

Oxford Univ Press2016

Contribution of the Arterial System and the Heart to Blood Pressure during Normal Aging - A Simulation Study

Nikolaos Stergiopoulos, Elira Maksuti, Nico Westerhof

During aging, systolic blood pressure continuously increases over time, whereas diastolic pressure first increases and then slightly decreases after middle age. These pressure changes are usually explained by changes of the arterial system alone (increase ...

Public Library of Science2016

Metabolomics-assisted proteomics identifies succinylation and SIRT5 as important regulators of cardiac function

Johan Auwerx, Zhi Li, Wei Chen, Dongryeol Ryu, Shuo Zhang

Cellular metabolites, such as acyl-CoA, can modify proteins, leading to protein posttranslational modifications (PTMs). One such PTM is lysine succinylation, which is regulated by sirtuin 5 (SIRT5). Although numerous proteins are modified by lysine succiny ...

Natl Acad Sciences2016

Methods for reliable estimation of pulse transit time and blood pressure variations using smartphone sensors

David Atienza Alonso, Francisco Javier Rincon Vallejos, Srinivasan Murali, Alair Dias Junior

Hypertension is known to affect around one third of adults globally and early diagnosis is essential to reduce the effects of this affliction. Today’s Blood Pressure (BP) monitoring cuffs are obtrusive and in- convenient for performing regular measurements ...

Elsevier Science Bv2016

Graph Chatbot

Chat with Graph Search

Ask any question about EPFL courses, lectures, exercises, research, news, etc. or try the example questions below.

DISCLAIMER: The Graph Chatbot is not programmed to provide explicit or categorical answers to your questions. Rather, it transforms your questions into API requests that are distributed across the various IT services officially administered by EPFL. Its purpose is solely to collect and recommend relevant references to content that you can explore to help you answer your questions.