Publications related to Heart valve

Latchable microfluidic valve arrays based on shape memory polymer actuators

We report arrays of latching microfluidic valves based on shape memory polymers (SMPs), and show their applications as reagent mixers and as peristaltic pumps. The valve design takes advantage of the SMP's multiple stable shapes and over a hundred-fold sti ...

2019

Propagation-based phase-contrast synchrotron imaging of aortic dissection in mice: from individual elastic lamella to 3D analysis

Nikolaos Stergiopoulos, Lydia Aslanidou, Bram Trachet, Marco Stampanoni, Patrick Segers

In order to show the advantage and potential of propagation-based phase-contrast synchrotron imaging in vascular pathology research, we analyzed aortic medial ruptures in BAPN/AngII-infused mice, a mouse model for aortic dissection. Ascending and thoraco-a ...

NATURE PUBLISHING GROUP2018

MATHICSE Technical Report : A complex blood flow patterns in an idealized left ventricle: a numerical study

Alfio Quarteroni, Luca Dede', Anna Tagliabue

In this paper, we study the blood flow dynamics in a three-dimensional (3D) idealized left ventricle of the human heart whose deformation is driven by muscle contraction and relaxation in coordination with the action of the mitral and aortic valves. We pro ...

MATHICSE2017

Complex blood flow patterns in an idealized left ventricle: A numerical study

Alfio Quarteroni, Anna Tagliabue

Amer Inst Physics2017

Fluid dynamics of an idealized left ventricle: the extended Nitsche's method for the treatment of heart valves as mixed time varying boundary conditions

Alfio Quarteroni, Anna Tagliabue

In this work, we study the blood flow dynamics in idealized left ventricles (LV) of the human heart modelled by the Navier-Stokes equations with mixed time varying boundary conditions. The latter are introduced for simulating the functioning of the aortic ...

Wiley2017

Integrated Heart-Coupling multiscale and multiphysics models for the simulation of the cardiac function

Alfio Quarteroni, Ricardo Esteban Ruiz Baier, Toni Mikael Lassila, Simone Rossi

Mathematical modeling of the human heart and its function can expand our understanding of various cardiac diseases, which remain the most common cause of death in the developed world. Like other physiological systems, the heart can be understood as a compl ...

Elsevier Science Sa2017

Notch1 haploinsufficiency causes ascending aortic aneurysms in mice

Freddy Radtke

An ascending aortic aneurysm (AscAA) is a life-threatening disease whose molecular basis is poorly understood. Mutations in NOTCH1 have been linked to bicuspid aortic valve (BAV), which is associated with AscAA. Here, we describe a potentially novel role f ...

Amer Soc Clinical Investigation Inc2017

A patient-specific aortic valve model based on moving resistive immersed implicit surfaces

Alfio Quarteroni, Elena Faggiano, Marco Fedele

In this paper, we propose a full computational framework to simulate the hemodynamics in the aorta including the valve. Closed and open valve surfaces, as well as the lumen aorta, are reconstructed directly from medical images using new ad hoc algorithms, ...

Springer Heidelberg2017

Cardiovascular morphometry with high-resolution 3D magnetic resonance: First application to left ventricle diastolic dysfunction

Nikolaos Stergiopoulos, Orestis Vardoulis, Davide Piccini

In this study, an image-based morphometry toolset quantifying geometric descriptors of the left ventricle, aorta and their coupling is applied to investigate whether morphological information can differentiate between subjects affected by diastolic dysfunc ...

Elsevier2017

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Heart valve

Latchable microfluidic valve arrays based on shape memory polymer actuators

Numerical approximation of cardiac electro-fluid-mechanical models

Propagation-based phase-contrast synchrotron imaging of aortic dissection in mice: from individual elastic lamella to 3D analysis

MATHICSE Technical Report : A complex blood flow patterns in an idealized left ventricle: a numerical study

Complex blood flow patterns in an idealized left ventricle: A numerical study

Fluid dynamics of an idealized left ventricle: the extended Nitsche's method for the treatment of heart valves as mixed time varying boundary conditions

Integrated Heart-Coupling multiscale and multiphysics models for the simulation of the cardiac function

Notch1 haploinsufficiency causes ascending aortic aneurysms in mice

A patient-specific aortic valve model based on moving resistive immersed implicit surfaces

Cardiovascular morphometry with high-resolution 3D magnetic resonance: First application to left ventricle diastolic dysfunction

Graph Chatbot

Chat with Graph Search

Latchable microfluidic valve arrays based on shape memory polymer actuators

Numerical approximation of cardiac electro-fluid-mechanical models

Fluid dynamics of an idealized left ventricle: the extended Nitsche's method for the treatment of heart valves as mixed time varying boundary conditions

Complex blood flow patterns in an idealized left ventricle: A numerical study

A patient-specific aortic valve model based on moving resistive immersed implicit surfaces

Propagation-based phase-contrast synchrotron imaging of aortic dissection in mice: from individual elastic lamella to 3D analysis

Integrated Heart-Coupling multiscale and multiphysics models for the simulation of the cardiac function

MATHICSE Technical Report : A complex blood flow patterns in an idealized left ventricle: a numerical study

Notch1 haploinsufficiency causes ascending aortic aneurysms in mice

Cardiovascular morphometry with high-resolution 3D magnetic resonance: First application to left ventricle diastolic dysfunction