Publications related to DNA polymerase

mu ABC: a systematic microsecond molecular dynamics study of tetranucleotide sequence effects in B-DNA

John Maddocks, Daiva Petkeviciute, Marco Pasi, Jonathan Mitchell

We present the results of microsecond molecular dynamics simulations carried out by the ABC group of laboratories on a set of B-DNA oligomers containing the 136 distinct tetranucleotide base sequences. We demonstrate that the resulting trajectories have ex ...

Oxford Univ Press2014

Quantitative Estimation of Biological Cell Surface Receptors by Segmenting Conventional Fluorescence Microscopy Images

Giovanni De Micheli, Sandro Carrara, Danilo Demarchi, Paolo Silacci, Julien Michel Ghaye, Chiara Succa, Guy Vergères

State-of-the-art techniques for measuring and monitoring gene level expression rely on messenger RNA (mRNA) extraction and quantification, usually based on the concept of reverse transcription polymerase chain reaction. In this paper, we take adva ...

Ieee2014

DNA Transport across the Outer and Inner Membranes of Naturally Transformable Vibrio cholerae Is Spatially but Not Temporally Coupled

Melanie Blokesch, Patrick Martin Seitz

The physiological state of natural competence for transformation allows certain bacteria to take up free DNA from the environment and to recombine such newly acquired DNA into their chromosomes. However, even though conserved components that are required t ...

American Society for Microbiology2014

Characteristic bimodal profiles of RNA polymerase II at thousands of active mammalian promoters

Felix Naef, Cédric Gobet, Kyle Gustafson, Mathieu Quinodoz

Background: In mammals, ChIP-seq studies of RNA polymerase II (PolII) occupancy have been performed to reveal how recruitment, initiation and pausing of PolII may control transcription rates, but the focus is rarely on obtaining finely resolved profiles th ...

BioMed Central2014

Composition of the DNA-uptake complex of Vibrio cholerae

Melanie Blokesch, Lisa Christina Metzger

Natural competence for transformation is a developmental program that allows certain bacteria to take up free extracellular DNA from the environment and integrate this DNA into their genome. Thereby, natural transformation acts as mode of horizontal gene t ...

2014

ComEA Is Essential for the Transfer of External DNA into the Periplasm in Naturally Transformable Vibrio cholerae Cells

Aleksandra Radenovic, Matteo Dal Peraro, Melanie Blokesch, Lorenz Jan Steinbock, Roman Bulushev, Patrick Martin Seitz, Hasan Pezeshgi Modarres

The DNA uptake of naturally competent bacteria has been attributed to the action of DNA uptake machineries resembling type IV pilus complexes. However, the protein(s) for pulling the DNA across the outer membrane of Gram-negative bacteria remain speculativ ...

Public Library Science2014

Dielectrophoresis of lambda-DNA using 3D carbon electrodes

Philippe Renaud, Rodrigo Martinez Duarte

Carbon electrodes have recently been introduced as an alternative to metal electrodes and insulator structures for dielectrophoretic applications. Here, an experimental and theoretical study employing an array of 3D carbon electrodes contained in a microfl ...

Wiley-Blackwell2013

Molecular basis of telomere syndrome caused by CTC1 mutations

Joachim Lingner, Jana Majerská, Liuh-Yow Chen

Mutations in CTC1 lead to the telomere syndromes Coats Plus and dyskeratosis congenita (DC), but the molecular mechanisms involved remain unknown. CTC1 forms with STN1 and TEN1 a trimeric complex termed CST, which binds ssDNA, promotes telomere DNA synthes ...

Cold Spring Harbor Laboratory Press2013

Telomere Length Homeostasis Responds to Changes in Intracellular dNTP Pools

Joachim Lingner, Shruti Sharma

Telomeres, the ends of linear eukaryotic chromosomes, shorten due to incomplete DNA replication and nucleolytic degradation. Cells counteract this shortening by employing a specialized reverse transcriptase called telomerase, which uses deoxyribonucleoside ...

Genetics Soc Am2013

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DNA polymerase

mu ABC: a systematic microsecond molecular dynamics study of tetranucleotide sequence effects in B-DNA

Quantitative Estimation of Biological Cell Surface Receptors by Segmenting Conventional Fluorescence Microscopy Images

DNA Transport across the Outer and Inner Membranes of Naturally Transformable Vibrio cholerae Is Spatially but Not Temporally Coupled

Characteristic bimodal profiles of RNA polymerase II at thousands of active mammalian promoters

TREX1 Deficiency Triggers Cell-Autonomous Immunity in a cGAS-Dependent Manner

Composition of the DNA-uptake complex of Vibrio cholerae

ComEA Is Essential for the Transfer of External DNA into the Periplasm in Naturally Transformable Vibrio cholerae Cells

Dielectrophoresis of lambda-DNA using 3D carbon electrodes

Molecular basis of telomere syndrome caused by CTC1 mutations

Telomere Length Homeostasis Responds to Changes in Intracellular dNTP Pools

Graph Chatbot

Chat with Graph Search

Dielectrophoresis of lambda-DNA using 3D carbon electrodes

DNA Transport across the Outer and Inner Membranes of Naturally Transformable Vibrio cholerae Is Spatially but Not Temporally Coupled

Composition of the DNA-uptake complex of Vibrio cholerae

Molecular basis of telomere syndrome caused by CTC1 mutations

mu ABC: a systematic microsecond molecular dynamics study of tetranucleotide sequence effects in B-DNA

Quantitative Estimation of Biological Cell Surface Receptors by Segmenting Conventional Fluorescence Microscopy Images

Characteristic bimodal profiles of RNA polymerase II at thousands of active mammalian promoters

ComEA Is Essential for the Transfer of External DNA into the Periplasm in Naturally Transformable Vibrio cholerae Cells

Telomere Length Homeostasis Responds to Changes in Intracellular dNTP Pools

TREX1 Deficiency Triggers Cell-Autonomous Immunity in a cGAS-Dependent Manner