Publications related to Antibiotic misuse

Capsular Polysaccharide Restrains Type VI Secretion in Acinetobacter baumannii

Melanie Blokesch, Loriane Bader, Mary-Claude Croisier-Coeytaux, Nicolas Olmo Flaugnatti

The type VI secretion system (T6SS) is a sophisticated, contact-dependent nanomachine involved in interbacterial competition. To function effectively, the T6SS must penetrate the membranes of both attacker and target bacteria. Structures associated with th ...

2024

Systematic mapping of antibiotic cross-resistance and collateral sensitivity with chemical genetics

Camille Véronique Bernadette Goemans, Florian Huber

By acquiring or evolving resistance to one antibiotic, bacteria can become resistant to a second one, due to shared underlying mechanisms. This is called cross-resistance (XR) and further limits therapeutic choices. The opposite scenario, in which initial ...

2024

Bactericidal effect of tetracycline in E. coli strain ED1a may be associated with ribosome dysfunction

Camille Véronique Bernadette Goemans, Christian Eugen Zimmerli, Martin Beck

Ribosomes translate the genetic code into proteins. Recent technical advances have facilitated in situ structural analyses of ribosome functional states inside eukaryotic cells and the minimal bacterium Mycoplasma. However, such analyses of Gram-negative b ...

2024

Implementing water recirculation in a novel portable plasma-activated water reactor enhances antimicrobial effect against Escherichia coli

Ivo Furno, Alan Howling, Fabio Avino, Rita Agus, Brayden Graham Myers, Lorenzo Ibba, Leonardo Zampieri

The need for sustainable and reliable decontamination methods is driven by concerns regarding antibiotic resistance, as well as environmental and cost -efficiency challenges associated with traditional methods. Plasmaactivated water (PAW) holds significant ...

Elsevier Science Sa2024

Homogeneous vs. heterogeneous photo-Fenton elimination of antibiotic-resistant bacteria bearing intracellular or extracellular resistance: Do resistance mechanisms interfere with disinfection pathways?

César Pulgarin, Stefanos Giannakis, Truong-Thien Melvin Le, Jérémie Decker

The present study aimed to fill the knowledge gap between the implications of intracellular and extracellular antibiotic resistance mechanisms may inflict on the inactivation pathways of the photo-Fenton process under mild conditions. It was thus designed ...

London2024

Machine learning method for the classification of the state of living organisms' oscillations

Sandor Kasas, María Inés Villalba

The World Health Organization highlights the urgent need to address the global threat posed by antibiotic-resistant bacteria. Efficient and rapid detection of bacterial response to antibiotics and their virulence state is crucial for the effective treatmen ...

Frontiers Media Sa2024

Simple optical nanomotion method for single-bacterium viability and antibiotic response testing

Sandor Kasas, María Inés Villalba, Allan Bonvallat, Eugenia Rossetti

Antibiotic resistance is nowadays a major public health issue. Rapid antimicrobial susceptibility tests (AST) are one of the options to fight this deadly threat. Performing AST with single-cell sensitivity that is rapid, cheap, and widely accessible, is ch ...

NATL ACAD SCIENCES2023

Biofilm formation on human immune cells is a multicellular predation strategy of Vibrio cholerae

Alexandre Louis André Persat, Sofya Mikhaleva

Biofilm formation is generally recognized as a bacterial defense mechanism against environmental threats, including antibiotics, bacteriophages, and leukocytes of the human immune system. Here, we show that for the human pathogen Vibrio cholerae, biofilm f ...

CELL PRESS2023

DNA modifications impact natural transformation of Acinetobacter baumannii

Melanie Blokesch, Nicolas Jean Philippe Guex, Christian Iseli, Alexandre Lemopoulos, Nina Vesel

Acinetobacter baumannii is a dangerous nosocomial pathogen, especially due to its ability to rapidly acquire new genetic traits, including antibiotic resistance genes (ARG). In A. baumannii, natural competence for transformation, one of the primary modes o ...

2023

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Antibiotic misuse

Capsular Polysaccharide Restrains Type VI Secretion in Acinetobacter baumannii

Systematic mapping of antibiotic cross-resistance and collateral sensitivity with chemical genetics

Bactericidal effect of tetracycline in E. coli strain ED1a may be associated with ribosome dysfunction

Implementing water recirculation in a novel portable plasma-activated water reactor enhances antimicrobial effect against Escherichia coli

Homogeneous vs. heterogeneous photo-Fenton elimination of antibiotic-resistant bacteria bearing intracellular or extracellular resistance: Do resistance mechanisms interfere with disinfection pathways?

Machine learning method for the classification of the state of living organisms' oscillations

Simple optical nanomotion method for single-bacterium viability and antibiotic response testing

Biofilm formation on human immune cells is a multicellular predation strategy of Vibrio cholerae

Glacier-Fed Stream Biofilms Harbor Diverse Resistomes and Biosynthetic Gene Clusters

DNA modifications impact natural transformation of Acinetobacter baumannii

Graph Chatbot

Chat with Graph Search

Systematic mapping of antibiotic cross-resistance and collateral sensitivity with chemical genetics

Bactericidal effect of tetracycline in E. coli strain ED1a may be associated with ribosome dysfunction

Homogeneous vs. heterogeneous photo-Fenton elimination of antibiotic-resistant bacteria bearing intracellular or extracellular resistance: Do resistance mechanisms interfere with disinfection pathways?

Simple optical nanomotion method for single-bacterium viability and antibiotic response testing

Machine learning method for the classification of the state of living organisms' oscillations

Capsular Polysaccharide Restrains Type VI Secretion in Acinetobacter baumannii

Implementing water recirculation in a novel portable plasma-activated water reactor enhances antimicrobial effect against Escherichia coli

Biofilm formation on human immune cells is a multicellular predation strategy of Vibrio cholerae

Glacier-Fed Stream Biofilms Harbor Diverse Resistomes and Biosynthetic Gene Clusters

DNA modifications impact natural transformation of Acinetobacter baumannii