Concept
Ulcer (dermatology)
Related publications (14)
Hypoxia Impairs Skin Myofibroblast Differentiation and Function
Boris Hinz, Giorgio Pietramaggiori
Ischemic wounds are characterized by oxygen levels lower than that of healthy skin ( hypoxia) and poor healing. To better understand the pathophysiology of impaired wound healing, we investigated how switching from high ( 21%) to low ( 2%) oxygen levels di ...
Nature Publishing Group2010Wound-healing defect of CD18(-/-) mice due to a decrease in TGF-beta1 and myofibroblast differentiation
We studied the mechanisms underlying the severely impaired wound healing associated with human leukocyte-adhesion deficiency syndrome-1 (LAD1) using a murine disease model. In CD18(-/-) mice, healing of full-thickness wounds was severely delayed during gra ...
Nature Publishing Group2005Stability of Ag nanoparticles dispersed in amphiphilic organic matrix
Philippe Buffat, Elena Suvorova Buffat
Nano- and thin-film technologies based on novel systems associating metals particles to polymer matrix open a broad range of different applications. Such composites were found to be more efficient and safe, for instance, in biomedical needs. The Ag/poly(N- ...
2005Impaired skin wound healing in peroxisome proliferator-activated receptor (PPAR)alpha and PPARbeta mutant mice
Denis Duboule, Jozsef Zakany, Walter Wahli
We show here that the alpha, beta, and gamma isotypes of peroxisome proliferator-activated receptor (PPAR) are expressed in the mouse epidermis during fetal development and that they disappear progressively from the interfollicular epithelium after birth. ...
2001