Skin and skin structure infection

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Supported photocatalysts for model pollutant degradation and bacterial inactivation : preparation, evaluation and characterization

Water quality and bacterial infections are directly related to human health and wellbeing, thus waste water treatment is a necessary procedure for avoiding disturbances to ecosystems and for assuring human health. Furthermore, bacterial contamination in wa ...

EPFL2017

New methods for developing (bi)cyclic peptides by phage display

Camille Villequey

Cyclic peptide ligands are a promising molecular format for the development of therapeutics. They combine some of the advantages of large protein therapeutics (high affinity and specificity) and of small molecule drugs (accessibility to chemical synthesis ...

EPFL2017

Inhibition of Sepiapterin Reductase through Formation of a Ternary Complex with Sulfasalazine or other Sulfa Drugs and NADP+

Miriam Grønlund Pedersen

The mechanism of action of sulfasalazine, an anti-inflammatory drug used against inflammatory bowel diseases and rheumatoid arthritis is, despite its medical importance, still not well understood. Recently, it was shown that sulfasalazine and its metabolit ...

EPFL2014

The contribution of the host stress response to the pathogenesis of Pseudomonas entomophila in the Drosophila intestine

Sveta Chakrabarti

Recently, several studies done in Drosophila have revealed that efficient and rapid recovery from bacterial infection in the gut is possible only when bacterial clearance by the immune system is coordinated with repair through renewal of the epithelium dam ...

EPFL2013

Genetic ablation of Drosophila phagocytes reveals their contribution to both development and resistance to bacterial infection

Bruno Lemaitre

Drosophila phagocytes participate in development and immune responses through their abilities to perform phagocytosis and/or secrete extra-cellular matrix components, antimicrobial peptides, clotting factors and signalling molecules. However, our knowledge ...

2009

Microbial phenotypic heterogeneity and antibiotic tolerance

John McKinney, Neeraj Dhar

Phenotypic heterogeneity, defined as metastable variation in cellular parameters generated by epigenetic mechanisms, is crucial for the persistence of bacterial populations under fluctuating selective pressures. Diversity ensures that some individuals will ...

2007

Stability of Ag nanoparticles dispersed in amphiphilic organic matrix

Philippe Buffat, Elena Suvorova Buffat

Nano- and thin-film technologies based on novel systems associating metals particles to polymer matrix open a broad range of different applications. Such composites were found to be more efficient and safe, for instance, in biomedical needs. The Ag/poly(N- ...

2005

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Inhibition of Sepiapterin Reductase through Formation of a Ternary Complex with Sulfasalazine or other Sulfa Drugs and NADP+

Miriam Grønlund Pedersen

EPFL2014

Supported photocatalysts for model pollutant degradation and bacterial inactivation : preparation, evaluation and characterization

Laura Victoria Suárez Murillo

EPFL2017

Genetic ablation of Drosophila phagocytes reveals their contribution to both development and resistance to bacterial infection

Bruno Lemaitre

2009

Stability of Ag nanoparticles dispersed in amphiphilic organic matrix

Philippe Buffat, Elena Suvorova Buffat

2005