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Conformational transitions have found broad interest due to their impact on protein misfolding and self-assembly as key events leading to the development of neurodegenerative diseases. However, investigation of these dynamic events has been limited so far ...
Restricted bioavailability of copper in certain environments can interfere with cellular respiration because copper is an essential cofactor of most terminal oxidases. The global response of the metabolically versatilebacterium and opportunistic pathogen P ...
A quick and reliable test was developed to measure the cyclization activity of cyclodextrin glycosyltransferases (CGT). Since the reproducibility depends mostly on the nature of the substrate, maltotriose was employed. The cyclodextrins formed are measured ...
The present study examines the interaction of amine- and carboxyl- PEG core/shell quantum dots (QDs) with metal resistant bacterium Cupriavidus metallidurans CH34. The evolution of the number of QDs, their hydrodynamic radius, diffusion coefficients and si ...
Aminoglycosides are powerful antibiotics, but the emergence of resistant bacterial strains has prompted the search for analogues with better pharmacological profiles. The synthesis of 2-deoxystreptamine (2-DOS) dimers linked by polyamines and analogues bas ...
Onset of the adaptive immune response in mice infected with Mycobacterium tuberculosis is accompanied by slowing of bacterial replication and establishment of a chronic infection. Stabilization of bacterial numbers during the chronic phase of infection is ...
This work deals with the creation of a stochastic algorithm for aa-tRNA competition during translation using an abstraction of the biological model. The major challenges were to manage aa-tRNA specie specific input information in order to deal with eventua ...
A review with 29 refs. of lab.-scale investigations carried out on the usefulness of biol. heat-release measurements, as a means for monitoring and controlling the metabolic state of microbial cultures. Such studies are carried out in high-quality bench-sc ...
