Publications related to Neutrophil

PEG/HA Hybrid Hydrogels for Biologically and Mechanically Tailorable Bone Marrow Organoids

Nicolas Antoine Vincent Broguiere, Martin Ehrbar, Queralt Vallmajó Martín

Bone marrow (BM) organoids provide powerful tools to study the vital interplay between the BM microenvironment and resident cells. Current biomaterials, however, are limited in terms of versatility for independently studying the biochemical and biophysical ...

WILEY-V C H VERLAG GMBH2020

In Vivo Pre-Instructed HSCs Robustly Execute Asymmetric Cell Divisions In Vitro

Matthias Lütolf, Aline Roch, Mukul Girotra, Vincent Trachsel

Hematopoietic stem cells (HSCs) are responsible for life-long production of all mature blood cells. Under homeostasis, HSCs in their native bone marrow niches are believed to undergo asymmetric cell divisions (ACDs), with one daughter cell maintaining HSC ...

MDPI2020

House dust mite drives proinflammatory eicosanoid reprogramming and macrophage effector functions

Nicola Harris, Julia Esser-von Bieren, Tiffany Babette Angélique Bouchery

Background Eicosanoid lipid mediators play key roles in type 2 immune responses, for example in allergy and asthma. Macrophages represent major producers of eicosanoids and they are key effector cells of type 2 immunity. We aimed to comprehensively track e ...

WILEY2019

The antimicrobial peptide defensin cooperates with tumour necrosis factor to drive tumour cell death in Drosophila

Bruno Lemaitre, Anna Dostalova

Antimicrobial peptides (AMPs) are small cationic molecules best known as mediators of the innate defence against microbial infection. While in vitro and ex vivo evidence suggest AMPs' capacity to kill cancer cells, in vivo demonstration of an anti-tumour r ...

ELIFE SCIENCES PUBLICATIONS LTD2019

Integrin-Mediated Macrophage Adhesion Promotes Lymphovascular Dissemination in Breast Cancer

Michele De Palma, Mario Leonardo Squadrito, Sina Nassiri

Lymphatic vasculature is crucial for metastasis in triple-negative breast cancer (TNBC); however, cellular and molecular drivers controlling lymphovascular metastasis are poorly understood. We define a macrophage-dependent signaling cascade that facilitate ...

CELL PRESS2019

Two Nimrod receptors, NimC1 and Eater, synergistically contribute to bacterial phagocytosis in Drosophila melanogaster

Bruno Lemaitre, Jan Paul Dudzic, Elodie Julie Virginie Ramond, Andrew Jonathan Bretscher, Claudia Melcarne

Eater and NimC1 are transmembrane receptors of the Drosophila Nimrod family, specifically expressed in haemocytes, the insect blood cells. Previous ex vivo and in vivoRNAi studies have pointed to their role in the phagocytosis of bacteria. Here, we have cr ...

WILEY2019

From Patients to Platelets and Back Again: Pharmacological Approaches to Glycoprotein VI, a Thrilling Antithrombotic Target with Minor Bleeding Risks

Nikolaos Stergiopoulos, Augusto Martins Lima

Despite significant advances in the treatment of thrombogenic diseases, antiplatelet therapies are still associated with a high bleeding risk. Consequently, potential benefits of preventing thromboembolic events by pharmacological agents need to be balance ...

GEORG THIEME VERLAG KG2019

A microfluidic cell-trapping device to study dynamic host-microbe interactions at the single-cell level

John McKinney, Matthieu Jean-Hubert Delincé, Chiara Toniolo

Single-cell imaging of host-microbe interactions over time is impeded by cellular motility because the cells under scrutiny tend to migrate out of the imaging field. To overcome this technical challenge, we developed a microfluidic platform for imaging hun ...

ELSEVIER ACADEMIC PRESS INC2018

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Neutrophil

PEG/HA Hybrid Hydrogels for Biologically and Mechanically Tailorable Bone Marrow Organoids

In Vivo Pre-Instructed HSCs Robustly Execute Asymmetric Cell Divisions In Vitro

House dust mite drives proinflammatory eicosanoid reprogramming and macrophage effector functions

The antimicrobial peptide defensin cooperates with tumour necrosis factor to drive tumour cell death in Drosophila

Integrin-Mediated Macrophage Adhesion Promotes Lymphovascular Dissemination in Breast Cancer

Two Nimrod receptors, NimC1 and Eater, synergistically contribute to bacterial phagocytosis in Drosophila melanogaster

From Patients to Platelets and Back Again: Pharmacological Approaches to Glycoprotein VI, a Thrilling Antithrombotic Target with Minor Bleeding Risks

A microfluidic cell-trapping device to study dynamic host-microbe interactions at the single-cell level

An Exploratory Study On The Functional Significance Of Eosinophil Residency In The Small Intestine Under Homeostatic Conditions

The role of Snail in non-small cell lung cancer

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Chat with Graph Search

An Exploratory Study On The Functional Significance Of Eosinophil Residency In The Small Intestine Under Homeostatic Conditions

PEG/HA Hybrid Hydrogels for Biologically and Mechanically Tailorable Bone Marrow Organoids

Integrin-Mediated Macrophage Adhesion Promotes Lymphovascular Dissemination in Breast Cancer

In Vivo Pre-Instructed HSCs Robustly Execute Asymmetric Cell Divisions In Vitro

House dust mite drives proinflammatory eicosanoid reprogramming and macrophage effector functions

Two Nimrod receptors, NimC1 and Eater, synergistically contribute to bacterial phagocytosis in Drosophila melanogaster

A microfluidic cell-trapping device to study dynamic host-microbe interactions at the single-cell level

The role of Snail in non-small cell lung cancer

From Patients to Platelets and Back Again: Pharmacological Approaches to Glycoprotein VI, a Thrilling Antithrombotic Target with Minor Bleeding Risks

The antimicrobial peptide defensin cooperates with tumour necrosis factor to drive tumour cell death in Drosophila