Publications related to Restriction enzyme

Practical Considerations for Improving the Productivity of Mass Spectrometry-based Proteomics

Yury Tsybin, Anton Kozhinov, Luca Fornelli, Kristina Srzentic, Unige Anna Laskay, Oxana Upir

Mass spectrometry (MS) is currently the most sensitive and selective analytical technique for routine peptide and protein structure analysis. Top-down proteomics is based on tandem mass spectrometry (MS/MS) of intact proteins, where multiply charged precur ...

Schweizerische Chemische Gesellschaft2013

PyroTRF-ID: a novel bioinformatics methodology for the affiliation of terminal-restriction fragments using 16S rRNA gene pyrosequencing data

Christof Holliger, Julien Maillard, Pierre Rossi, Jacques Rougemont, David Gregory Weissbrodt, Noam Shani, Lucas Sinclair

Background: In molecular microbial ecology, massive sequencing is gradually replacing classical fingerprinting techniques such as terminal-restriction fragment length polymorphism (T-RFLP) combined with cloning-sequencing for the characterization of microb ...

BioMed Central2012

PyroTRF-ID: a novel bioinformatics approach for the identification of terminal-restriction fragments using microbiome pyrosequencing data

Christof Holliger, Julien Maillard, Pierre Rossi, Jacques Rougemont, David Gregory Weissbrodt, Noam Shani, Lucas Sinclair

Aim: In molecular microbial ecology, pyrosequencing is gradually supplanting classical fingerprinting techniques such as terminal-restriction fragment length polymorphism (T-RFLP) combined with cloning-sequencing for enhanced characterization of microbiome ...

2012

Global Solutions to a Non-Local Diffusion Equation with Quadratic Non-Linearity

Joachim Krieger

In this paper we prove the global in time well-posedness of the following non-local diffusion equation with

\alpha\, \varepsilon [0, 2/3)

\partial_tu=\{(-\Delta)^{-1}u\}\Delta u+\alpha u^2, \,\, u(t=0)=u_0

. The initial condition

u_0

is positive, rad ...

2012

UV radiation induces genome-mediated, site-specific cleavage in viral protein

Tamar Kohn, Yury Tsybin, Laure Menin, Krista Rule Wigginton, Michele Cascella, Hisham Ben Hamidane, Anne Thérèse Sigstam

Much research has been dedicated to understanding the molecular basis of UV damage to biomolecules, yet many questions remain regarding the specific pathways involved. Here we describe a genome-mediated mechanism that causes sitespecific virus protein clea ...

2012

Functional diversity of reductive dehalogenases in a bacterial consortium degrading chloroethenes

Christof Holliger, Julien Maillard, Géraldine Florence Buttet

Several enrichment cultures were investigated in our laboratory for the bioremediation potential of tetrachloroethene (PCE). The underlying process, organohalide respiration (OHR), is based on bacterial anaerobic respiration in which the chlorinated compou ...

2012

Structure and function of the transketolase from Mycobacterium tuberculosis and comparison with the human enzyme

Stewart Cole, Florence Pojer, Elizabeth Fullam

The transketolase (TKT) enzyme in Mycobacterium tuberculosis represents a novel drug target for tuberculosis treatment and has low homology with the orthologous human enzyme. Here, we report on the structural and kinetic characterization of the transketola ...

Royal Soc2012

Functional diversity of reductive dehalogenases in a bacterial consortium degrading chloroethenes

Christof Holliger, Julien Maillard, Géraldine Florence Buttet

Enrichment cultures are investigated for the bioremediation potential of tetrachloroethene (PCE). This process is based on anaerobic respiration in which chlorinated compounds are used as electron acceptors (organohalide respiration, OHR). The key enzyme i ...

2012

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Global Solutions to a Non-Local Diffusion Equation with Quadratic Non-Linearity

Joachim Krieger

In this paper we prove the global in time well-posedness of the following non-local diffusion equation with

\alpha\, \varepsilon [0, 2/3)

\partial_tu=\{(-\Delta)^{-1}u\}\Delta u+\alpha u^2, \,\, u(t=0)=u_0

. The initial condition

u_0

is positive, rad ...

2012

Restriction enzyme

The DprE1 enzyme, one of the most vulnerable targets of Mycobacterium tuberculosis

Practical Considerations for Improving the Productivity of Mass Spectrometry-based Proteomics

PyroTRF-ID: a novel bioinformatics methodology for the affiliation of terminal-restriction fragments using 16S rRNA gene pyrosequencing data

PyroTRF-ID: a novel bioinformatics approach for the identification of terminal-restriction fragments using microbiome pyrosequencing data

Global Solutions to a Non-Local Diffusion Equation with Quadratic Non-Linearity

Assessing the Bacterial Ecology of Organohalide Respiration for the Design of Bioremediation Strategies

UV radiation induces genome-mediated, site-specific cleavage in viral protein

Functional diversity of reductive dehalogenases in a bacterial consortium degrading chloroethenes

Structure and function of the transketolase from Mycobacterium tuberculosis and comparison with the human enzyme

Functional diversity of reductive dehalogenases in a bacterial consortium degrading chloroethenes

Graph Chatbot

Chat with Graph Search

The DprE1 enzyme, one of the most vulnerable targets of Mycobacterium tuberculosis

Global Solutions to a Non-Local Diffusion Equation with Quadratic Non-Linearity

PyroTRF-ID: a novel bioinformatics approach for the identification of terminal-restriction fragments using microbiome pyrosequencing data

Practical Considerations for Improving the Productivity of Mass Spectrometry-based Proteomics

Assessing the Bacterial Ecology of Organohalide Respiration for the Design of Bioremediation Strategies

UV radiation induces genome-mediated, site-specific cleavage in viral protein

Functional diversity of reductive dehalogenases in a bacterial consortium degrading chloroethenes

Structure and function of the transketolase from Mycobacterium tuberculosis and comparison with the human enzyme

Functional diversity of reductive dehalogenases in a bacterial consortium degrading chloroethenes

PyroTRF-ID: a novel bioinformatics methodology for the affiliation of terminal-restriction fragments using 16S rRNA gene pyrosequencing data