Concept

Central pattern generator

Related publications (168)

Whisking-Related Changes in Neuronal Firing and Membrane Potential Dynamics in the Somatosensory Thalamus of Awake Mice

The thalamus transmits sensory information to the neocortex and receives neocortical, subcortical, and neuromodulatory inputs. Despite its obvious importance, surprisingly little is known about thalamic function in awake animals. Here, using intracellular ...

Elsevier2015

Muscle Spindle Feedback Directs Locomotor Recovery and Circuit Reorganization after Spinal Cord Injury

Grégoire Courtine, Isabel Laura Vollenweider

Spinal cord injuries alter motor function by disconnecting neural circuits above and below the lesion, rendering sensory inputs a primary source of direct external drive to neuronal networks caudal to the injury. Here, we studied mice lacking functional mu ...

Elsevier2014

Neurorehabilitation and neuroprosthetic technologies to regain motor function following spinal cord injury

Rubia van den Brand

Spinal cord injury (SCI) leads to a range of disabilities, including locomotor impairments that seriously diminish the patients’ quality of life. Strategies to promote functional recovery after severe SCI will undoubtedly include approaches to regenerate i ...

ETH Zurich2014

Cortical Control of Whisker Movement

Carl Petersen

Facial muscles drive whisker movements, which are important for active tactile sensory perception in mice and rats. These whisker muscles are innervated by cholinergic motor neurons located in the lateral facial nucleus. The whisker motor neurons receive s ...

Annual Reviews2014

Evolving Hox Activity Profiles Govern Diversity in Locomotor Systems

Denis Duboule

The emergence of limb-driven locomotor behaviors was a key event in the evolution of vertebrates and fostered the transition from aquatic to terrestrial life. We show that the generation of limb-projecting lateral motor column (LMC) neurons in mice relies ...

Elsevier2014

Gait Control and Locomotor Recovery after Spinal Cord Injury

The gait of patients with an incomplete spinal cord injury (iSCI) has been studied previously. The most widely examined parameters to characterize iSCI gait are walking speed and time-distance measures (e.g., step length, step frequency, gait-cycle phases) ...

ETH Zurich2014

A doppler effect in embryonic pattern formation

Andrew Charles Oates, Daniele Soroldoni

During embryonic development, temporal and spatial cues are coordinated to generate a segmented body axis. In sequentially segmenting animals, the rhythm of segmentation is reported to be controlled by the time scale of genetic oscillations that periodical ...

2014

Neural generators of psychogenic seizures: Evidence from intracranial and extracranial brain recordings

Olaf Blanke, Pär Halje

Psychogenic seizures (PSs) convincingly mimic seizure phenomena but with no underlying epileptic activity. However, not much is known about their neurophysiological basis. We had the rare opportunity to analyze intracranial brain recordings of PSs occurrin ...

2014

Modeling a diversity of salamander motor behaviors with coupled abstract oscillators and a robot

Jérémie Knüsel

Salamanders are capable of a variety of locomotor behaviors including swimming, underwater stepping, and forward and backward land stepping. According to electromyographic and kinematic recordings of the trunk, each of these behaviors is characterized by a ...

EPFL2013

A Salamander’s Flexible Spinal Network for Locomotion, Modeled at Two Levels of Abstraction

Auke Ijspeert, Andrej Bicanski, Jérémie Knüsel

Animals have to coordinate a large number of muscles in different ways to efficiently move at various speeds and in different and complex environments. This coordination is in large part based on central pattern generators (CPGs). These neural networks are ...

Oxford University Press2013

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