Concept

Central pattern generator

Related publications (168)

Modeling spinal locomotor circuits for movements in developing zebrafish

Many spinal circuits dedicated to locomotor control have been identified in the developing zebrafish. How these circuits operate together to generate the various swimming movements during development remains to be clarified. In this study, we iteratively b ...

eLIFE SCIENCES PUBL LTD2021

Spinal V1 neurons inhibit motor targets locally and sensory targets distally

Yann Roussel

Rostro-caudal coordination of spinal motor output is essential for locomotion. Most spinal interneurons project axons longitudinally to govern locomotor output, yet their connectivity along this axis remains unclear. In this study, we use larval zebrafish ...

CELL PRESS2021

Personalizable computational models of electrical spinal cord stimulation to restore function after neurological disorders

Andreas Rowald

Spinal Cord Injury (SCI) disrupts the communication between the brain and spinal circuits below the lesion, leading to a plethora of neurological impairments, including the loss of motor function. At present, the only medical practices to enhance recovery ...

EPFL2021

Motor state transitions and Breathing in Brain Machine Interfaces

Bastien Orset

Brain-Machine interfaces aim to create a direct neural link between user's brain and machines. This goal has pushed scientists to investigate a large spectrum of applications in the realm of assistive and rehabilitation technologies. However, despite great ...

EPFL2021

Clustering and control for adaptation uncovers time-warped spike time patterns in cortical networks in vivo

James Bryden Isbister

How information in the nervous system is encoded by patterns of action potentials (i.e. spikes) remains an open question. Multi-neuron patterns of single spikes are a prime candidate for spike time encoding but their temporal variability requires further c ...

2021

Emergence of robust self-organized undulatory swimming based on local hydrodynamic force sensing

Auke Ijspeert, Kamilo Andres Melo Becerra, Robin Thandiackal, Laura Isabel Paez Coy, Kyoichi Akiyama

Undulatory swimming represents an ideal behavior to investigate locomotion control and the role of the underlying central and peripheral components in the spinal cord. Many vertebrate swimmers have central pattern generators and local pressure-sensitive re ...

AMER ASSOC ADVANCEMENT SCIENCE2021

Sprawling Quadruped Robot Driven by Decentralized Control With Cross-Coupled Sensory Feedback Between Legs and Trunk

Auke Ijspeert, Shura Suzuki

Quadruped animals achieve agile and highly adaptive locomotion owing to the coordination between their legs and other body parts, such as the trunk, head, and tail, that is, body-limb coordination. This study aims to understand the sensorimotor control und ...

FRONTIERS MEDIA SA2021

Effects of eight neuropsychiatric copy number variants on human brain structure

Bogdan Draganski, Lester Melie Garcia, Borja Rodriguez Herreros, Kuldeep Kumar, Claudia Modenato

Many copy number variants (CNVs) confer risk for the same range of neurodevelopmental symptoms and psychiatric conditions including autism and schizophrenia. Yet, to date neuroimaging studies have typically been carried out one mutation at a time, showing ...

SPRINGERNATURE2021

Dynamics of amygdala connectivity in bipolar disorders: a longitudinal study across mood states

Dimitri Nestor Alice Van De Ville, Thomas William Arthur Bolton, Maria Giulia Preti, Gwladys Rey, Julian Gaviria

Alterations in activity and connectivity of brain circuits implicated in emotion processing and emotion regulation have been observed during resting-state for different clinical phases of bipolar disorders (BD), but longitudinal investigations across diffe ...

SPRINGERNATURE2021

Corticolumbar dynamics during recovery after spinal cord injury

Selin Anil

In humans, a severe spinal cord contusion interrupts the vast majority of supraspinal projections to the spinal cord below the lesion. Permanent paralysis results from the chronic failure of these spared projections to engage lumbar circuits producing leg ...

EPFL2020

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