Related publications (32)

New insights into rodent brain microstructure and metabolism in hepatic encephalopathy

Jessie Julie Mosso

Type C hepatic encephalopathy (HE) is a severe neuropsychiatric complication of chronic liver disease, for which the prognosis is poor in the absence of liver transplantation. Cirrhosis in type C HE leads to a toxic accumulation of ammonia in the blood, wh ...
EPFL2023

The effects of time-restricted eating and weight loss on bone metabolism and health: a 6-month randomized controlled trial

Nicholas Edward Phillips, Alexandra Hemmer

Objective This study explored the impact of time-restricted eating (TRE) versus standard dietary advice (SDA) on bone health. Methods Adults with >= 1 component of metabolic syndrome were randomized to TRE (ad libitum eating within 12 hours) or SDA (food p ...
WILEY2022

Roadmap toward the 10 ps time-of-flight PET challenge

Edoardo Charbon, Mathieu Benoit, Christian Morel, Joao Varela

Since the seventies, positron emission tomography (PET) has become an invaluable medical molecular imaging modality with an unprecedented sensitivity at the picomolar level, especially for cancer diagnosis and the monitoring of its response to therapy. Mor ...
IOP PUBLISHING LTD2020

Flexoelectricity in Bones

Dragan Damjanovic

Bones generate electricity under pressure, and this electromechanical behavior is thought to be essential for bone’s self-repair and remodeling properties. The origin of this response is attributed to the piezoelectricity of collagen, which is the main str ...
2018

Randomized Projections for Improved Sensing and Imaging in Positron Emission Tomography

Positron Emission Tomography (PET) aims at recovering the metabolic activity of an organ of interest. Established algorithms implemented in contemporary PET scans are based on an approximation of the inverse Radon transform, resulting in a suboptimal estim ...
2017

In vitro and in vivo investigation of bisphosphonate-loaded hydroxyapatite particles for peri-implant bone augmentation

Dominique Pioletti, Ulrike Kettenberger

Locally applied bisphosphonates, such as Zoledronate, have been shown in several studies to inhibit peri-implant bone resorption and recently to enhance peri-implant bone formation. Studies have also demonstrated positive effects of hydroxyapatite particle ...
Wiley-Blackwell2017

Osteoblasts remotely supply lung tumors with cancer-promoting SiglecF(high) neutrophils

Etienne Meylan, Ferdinando Pucci, Julien Robert Rémi Faget

Bone marrow-derived myeloid cells can accumulate within tumors and foster cancer outgrowth. Local immune-neoplastic interactions have been intensively investigated, but the contribution of the systemic host environment to tumor growth remains poorly unders ...
Amer Assoc Advancement Science2017

The Necrosis-Avid Small Molecule HQ4-DTPA as a Multimodal Imaging Agent for Monitoring Radiation Therapy-Induced Tumor Cell Death

Riccardo Sinisi

Purpose: Most effective antitumor therapies induce tumor cell death. Non-invasive, rapid and accurate quantitative imaging of cell death is essential for monitoring early response to antitumor therapies. To facilitate this, we previously developed a biocom ...
Frontiers Media Sa2016

Targeting receptor activator of nuclear factor-kappa B as a new therapy for bone metastasis in non-small cell lung cancer

Etienne Meylan

Purpose of review The review aims at comprehensively discussing our current knowledge on bone metastases incidence in non-small cell lung cancer (NSCLC), their related complications as well as clinical impact in patients suffering from advanced disease. Re ...
Lippincott Williams & Wilkins2013

Differential X-ray phase contrast tomography of Alzheimer plaques in mouse models: perspectives for drug development and clinical imaging techniques

Peter Modregger, Marco Stampanoni

Alzheimer's disease (AD) is a looming threat on an ever-ageing population, with devastating effects on the human intellect. A particular characteristic lesion - the extracellular amyloid plaque - accumulates in the brain of AD patients during the course of ...
Institute of Physics2013

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