Concept

Molecular motor

Related publications (93)

DNA-segment-capture model for loop extrusion by structural maintenance of chromosome (SMC) protein complexes

Cells possess remarkable control of the folding and entanglement topology of long and flexible chromosomal DNA molecules. It is thought that structural maintenance of chromosome (SMC) protein complexes play a crucial role in this, by organizing long DNAs i ...

2019

A Unified View on Nanoscale Packing, Connectivity, and Conductivity of CNT Networks

Claudio Grimaldi

The design of functional structures from primary building blocks requires a thorough understanding of how size, shape, and particle-particle interactions steer the assembly process. Specifically, for electrically conductive networks build from carbon nanot ...

WILEY-V C H VERLAG GMBH2019

The Diverse Nature of Ion Speciation at the Nanoscale Hydrophobic/Water Interface

Sylvie Roke, Halil Ibrahim Okur, Evangelia Zdrali

Many biological systems are composed of nanoscale structures having hydrophobic and hydrophilic groups adjacent to one another and in contact with aqueous electrolyte solution. The interaction of ions with such structures is of fundamental importance. Alth ...

AMER CHEMICAL SOC2019

Scanning Probe-Directed Assembly and Rapid Chemical Writing Using Nanoscopic Flow of Phospholipids

Vytautas Navikas

Nanofluidic systems offer a huge potential for discovery of new molecular transport and chemical phenomena that can be employed for future technologies. Herein, we report on the transport behavior of surface-reactive compounds in a nanometer-scale flow of ...

AMER CHEMICAL SOC2019

Tumour exosomal CEMIP protein promotes cancer cell colonization in brain metastasis

Etienne Meylan, Loïc Steiner, Yuan Liu, Gonçalo Rodrigues

The development of effective therapies against brain metastasis is currently hindered by limitations in our understanding of the molecular mechanisms driving it. Here we define the contributions of tumour-secreted exosomes to brain metastatic colonization ...

NATURE PUBLISHING GROUP2019

Extending the Scope of the Density Overlap Region Indicator

Laurent Alexis Clément Vannay

In this thesis, original applications of the Density Overlap Region Indicator (DORI), a density dependent bonding descriptor capable of simultaneously capturing covalent and noncovalent interactions, are discussed. The use of scalar fields, such as DORI, w ...

EPFL2018

Probing Protein Dynamics Using Multifield Variable Temperature NMR Relaxation and Molecular Dynamics Simulation

David Lyndon Emsley, Albert Hofstetter, Nicola Salvi, Jayasubba Reddy Yarava, Baptiste Busi

Understanding the interplay between protein function and dynamics is currently one of the fundamental challenges of physical biology. Recently, a method using variable temperature solid-state nuclear magnetic resonance relaxation measurements has been prop ...

2018

Bistability, Oscillations, and Bidirectional Motion of Ensemble of Hydrodynamically Coupled Molecular Motors

We analyze the collective behavior of hydrodynamically coupled molecular motors. We show that the local fluxes induced by motor displacement can induce the experimentally observed bidirectional motion of cargoes and vesicles. By means of a mean-field appro ...

Amer Physical Soc2017

A multiscale study of the role of dynamin in the regulation of glucose uptake

Johan Auwerx, Martinus Gijs, Kristina Schoonjans, Laurent Mouchiroud, Raphaël Etienne Jean Trouillon, Keir Joe Menzies, Maria Cristina Letizia

Glucose uptake in muscle cells in response to insulin is a fundamental mechanism for metabolism. The inability of cells to mobilize the specific glucose transporter GLUT4 is believed to be at least partially accountable for diseases, like diabetes, where c ...

Royal Soc Chemistry2017

Impact of molecular flexibility on the site energy shift of chlorophylls in Photosystem II

Daniele Narzi, Leonardo Guidoni, Marco Manzoli

Light harvesting from the Sun by antenna complexes surrounding the reaction center of Photosystem II represents the first step of the natural oxygenic photosynthesis performed by plants, algae and cyanobacteria. The excitation energy derived from the sunli ...

Elsevier Science Bv2017

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