Concept
Kidney failure
Related publications (136)
Whole-heart electromechanical simulations using Latent Neural Ordinary Differential Equations
Alfio Quarteroni, Francesco Regazzoni, Luca Dede'
Cardiac digital twins provide a physics and physiology informed framework to deliver personalized medicine. However, high-fidelity multi-scale cardiac models remain a barrier to adoption due to their extensive computational costs. Artificial Intelligence-b ...
Nature Portfolio2024Iron-carbohydrate complexes treating iron anaemia: Understanding the nano-structure and interactions with proteins through orthogonal characterisation
Antonia Neels, Marianne Liebi, Tiberiu Totu
Intravenous (IV) iron-carbohydrate complexes are widely used nanoparticles (NPs) to treat iron deficiency anaemia, often associated with medical conditions such as chronic kidney disease, heart failure and various inflammatory conditions. Even though a ple ...
Elsevier2024Experimental characterization and stochastic models for time-dependent rupture of thin-ply composite laminates
Thin-laminate composites with thicknesses below 200 mu m hold significant promise for future, larger, and lighter deployable structures. This paper presents a study of the time-dependent failure behavior of thin carbon-fiber laminates under bending, focusi ...
2024Capsizing due to friction-induced twist in the failure of stopper knots
Pedro Miguel Nunes Pereira de Almeida Reis, Paul Johanns
We investigate the failure mechanism of stopper knots, with a particular focus on the figure -8 knot as a representative example. Stopper knots are widely used in climbing, sailing, racket stringing, and sewing to maintain tension in ropes, strings, or thr ...
Elsevier2024Roles of Clinical Features and Chest CT in Predicting the Outcomes of Hospitalized Patients with COVID-19 Developing AKI
Ali Falsafi, Shekoofeh Yaghmaei
This research aimed to evaluate the clinical features and computed tomography (CT) scans associated with poor outcomes in COVID-19 patients with acute kidney injury (AKI). A total of 351 COVID-19 patients (100 AKI, 251 non-AKI) hospitalized at Imam Hossein ...
IRANIAN SOC NEPHROLGY2023NAD(+) Metabolism and Interventions in Premature Renal Aging and Chronic Kidney Disease
Premature aging causes morphological and functional changes in the kidney, leading to chronic kidney disease (CKD). CKD is a global public health issue with far-reaching consequences, including cardio-vascular complications, increased frailty, shortened li ...
MDPI2023New roles of Bicc1 in cilia formation, cell adhesion, and in adult kidneys.
Bicaudal-C1 (Bicc1), an RNA-Binding protein, is a ciliopathy-associated protein. In development, Bicc1 is necessary for left-right axis specification. Loss of Bicc1 in mice also associates with polycystic kidney development. In human, two hereditary polycy ...
EPFL2023Effect of the structural modification of Candesartan with Zinc on hypertension and left ventricular hypertrophy
Nikolaos Stergiopoulos, Augusto Martins Lima, Valeria Romina Martinez
Hypertension is the most common cause of left ventricular hypertrophy, contributing to heart failure progression. Candesartan (Cand) is an angiotensin receptor antagonist widely used for hypertension treatment. Structural modifications were previously perf ...
ELSEVIER2023Cardiovascular response to closed-loop intraneural stimulation of the right vagus nerve: a proof-of-concept study
Vagus nerve stimulation (VNS) is an FDA-approved technique for the neuromodulation of the autonomic nervous system. There are many therapeutic applications where VNS could be used as a therapy, such as cardiovascular diseases, epilepsy, depression, and inf ...
New York2023