Concept

Blood sugar level

Related publications (228)

Fetal cells for intervertebral disc regeneration

Degeneration of the intervertebral disc (IVD) is thought to be one main factor in the development of back pain. It is not a symptom by itself but can lead to painful pathological conditions. Current treatments aim at relieving pain by conservative care, me ...

EPFL2009

Novel chemico-mechanical approach towards long-term implantable glucose sensing

Peter Ryser, Jean-Michel Sallese, Eric Meurville, Christophe Boss

The proof of concept of a continuously sensing affinity device based on the glucose-dependent viscosity of a sensitive solution containing dextran and Concanavalin A has been successfully demonstrated. The biosensor incorporates a piezoelectric diaphragm a ...

Elsevier2009

A synthetic membrane protein in tethered lipid bilayers for immunosensing in whole blood

Horst Vogel, Samuel Terrettaz, Solomzi Makohliso, Stéphanie Follonier

Tethered lipid bilayers, containing a transmembrane synthetic ligand-gated ion channel (SLIC), have been formed on gold surfaces. The SLIC was designed as a highly selective receptor and reporter protein to detect antibodies in whole blood, which are of im ...

Elsevier2009

Amperometric biosensor with nanostructured electrodes by using multi-alled carbon nanotubes for glucose detection in cell culture medium

Giovanni De Micheli, Sandro Carrara, Cristina Boero

The monitoring of metabolic compounds such as glucose is largely reported in literature. The applications of this type of analysis are mainly related to clinical purposes, e.g. in diabetes pathology, where a lot of studies are presented in literature. Rece ...

2009

Characterization of the erythrocyte response to glucose levels by impedance spectroscopy

Philippe Renaud, Thomas Michael Braschler, Guillaume Berlier

[...] For many years, researchers in the biosensors field have been trying to develop a device allowing the precise measurement of the glucose level through the intact skin. In this project, an efficient device was constructed for the in-vitro impedance me ...

2008

Non-invasive quantification of brain glycogen absolute concentration

Rolf Gruetter, Lijing Xin, Hongxia Lei, Ruud van Heeswijk, Hanne Frenkel, Sabrina Laus

The only currently available method to measure brain glycogen in vivo is C-13 NMR spectroscopy. Incorporation of C-13-labeled glucose (Glc) is necessary to allow glycogen measurement, but might be affected by turnover changes. Our aim was to measure glycog ...

Wiley-Blackwell2008

Glucose restriction: longevity SIRTainly, but without building muscle?

Johan Auwerx, Carlos Canto Alvarez

The two metabolic sensors AMPK and SIRT1 take center stage as Fulco et al. reveal, in this issue of Developmental Cell, the signaling mechanism by which low glucose prevents the correct development of the myogenic program. These observations may hold some ...

2008

Novel potent and selective bile acid derivatives as TGR5 agonists: biological screening, structure-activity relationships, and molecular modeling studies

Johan Auwerx, Kristina Schoonjans

TGR5, a metabotropic receptor that is G-protein-coupled to the induction of adenylate cyclase, has been recognized as the molecular link connecting bile acids to the control of energy and glucose homeostasis. With the aim of disclosing novel selective modu ...

2008

Human brain glycogen content and metabolism: Implications on its role in brain energy metabolism

Rolf Gruetter, Ajay Kumar

The adult brain relies on glucose for its energy needs and stores it in the form of glycogen, primarily in astrocytes. Animal and culture studies indicate that brain glycogen may support neuronal function when the glucose supply from the blood is inadequat ...

2007

Evaluation of glucose homeostasis

Johan Auwerx

Obesity and dyslipidemia are often found in association with insulin resistance (IR). These components combined with hypertension characterize the most common endocrine disorder in humans, the metabolic syndrome. Thus, in addition to profiling body weight ...

Wiley2007

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