Concept

Central tolerance

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Central tolerance

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Early-life vitamin A treatment rescues neonatal infection-induced durably impaired tolerogenic properties of celiac lymph nodes

Autoantibodies against type I IFNs in humans with alternative NF-κB pathway deficiency

Reaching an understanding of cortico-medullary control of forelimb behaviors

Stromal Notch ligands foster lymphopenia-driven functional plasticity and homeostatic proliferation of naive B cells

Notch1-driven T-ALL chromatin landscape is regulated by Tcf1 in hematopoietic progenitors

Follicular regulatory helper T cells control the response of regulatory B cells to a high-cholesterol diet

Systematic screening of viral and human genetic variation identifies antiretroviral resistance and immune escape link

Regulatory T cells engineered with TCR signaling-responsive IL-2 nanogels suppress alloimmunity in sites of antigen encounter

Canonical Notch signaling controls the early thymic epithelial progenitor cell state and emergence of the medullary epithelia lineage in fetal thymus development

In Vivo Pre-Instructed HSCs Robustly Execute Asymmetric Cell Divisions In Vitro