In male human anatomy, the foreskin, also known as the prepuce (ˈpriːpjuːs), is the double-layered fold of skin, mucosal and muscular tissue at the distal end of the human penis that covers the glans and the urinary meatus. The foreskin is attached to the glans by an elastic band of tissue, known as the frenulum. The outer skin of the foreskin meets with the inner preputial mucosa at the area of the mucocutaneous junction. The foreskin is mobile, fairly stretchable and sustains the glans in a moist environment. Except for humans, a similar structure, known as penile sheath, appears in the male sexual organs of all primates and the vast majority of mammals. In humans, foreskin length varies widely and coverage of the glans in a flaccid and erect state can also vary. The foreskin is fused to the glans at birth and is generally not retractable in infancy and early childhood. Inability to retract the foreskin in childhood should not be considered a problem unless there are other symptoms. Retraction of the foreskin is not recommended until it loosens from the glans before or during puberty. In adults, it is typically retractable over the glans, given normal development. The male prepuce is anatomically homologous to the clitoral hood in females. In some cases, the foreskin may become subject to a pathological condition. The outside of the foreskin is a continuation of the shaft skin of the penis and is covered by a keratinized stratified squamous epithelium. The inner foreskin is a continuation of the epithelium that covers the glans and is made up of glabrous squamous mucous membrane, like the inside of the eyelid or the mouth. The mucosal aspect of the prepuce has a great capacity for self-repair. The area of the outer foreskin measures 7–100 cm2, and the inner foreskin measures 18–68 cm.2 The mucocutaneous zone occurs where the outer and inner foreskin meet. The foreskin is free to move after it separates from the glans, which usually occurs before or during puberty.

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