The Americas, sometimes collectively called America, are a landmass comprising the totality of North and South America. The Americas make up most of the land in Earth's Western Hemisphere and comprise the New World. Along with their associated islands, the Americas cover 8% of Earth's total surface area and 28.4% of its land area. The topography is dominated by the American Cordillera, a long chain of mountains that runs the length of the west coast. The flatter eastern side of the Americas is dominated by large river basins, such as the Amazon, St. Lawrence River–Great Lakes basin, Mississippi, and La Plata. Since the Americas extend from north to south, the climate and ecology vary widely, from the arctic tundra of Northern Canada, Greenland, and Alaska, to the tropical rain forests in Central America and South America. Humans first settled the Americas from Asia between 20,000 and 16,000 years ago. A second migration of Na-Dene speakers followed later from Asia. The subsequent migration of the Inuit into the neoarctic around 3500 BCE completed what is generally regarded as the settlement by the indigenous peoples of the Americas. The first known European settlement in the Americas was by the Norse explorer Leif Erikson. However, the colonization never became permanent and was later abandoned. The Spanish voyages of Christopher Columbus from 1492 to 1504 resulted in permanent contact with European (and subsequently, other Old World) powers, which eventually led to the Columbian exchange and inaugurated a period of exploration, conquest, and colonization whose effects and consequences persist to the present. The Spanish presence involved the enslavement of large numbers of the indigenous population of America. Diseases introduced from Europe and West Africa devastated the indigenous peoples, and the European powers colonized the Americas. Mass emigration from Europe, including large numbers of indentured servants, and importation of African slaves largely replaced the indigenous peoples.

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