Concept

Structural genomics

Related publications (230)

Coiled coils: attractive protein folding motifs for the fabrication of self-assembled, responsive and bioactive materials

The coiled coil is a superhelical protein structural motif that consists of two or more alpha-helical peptides that are wrapped around each other in superhelical fashion. Coiled coils are amongst the most ubiquitous folding motifs found in proteins and hav ...

Royal Society of Chemistry2010

Structural determination of biomolecular interfaces by nuclear magnetic resonance of proteins with reduced proton density

Fabien Ferrage

Protein interactions are important for understanding many molecular mechanisms underlying cellular processes. So far, interfaces between interacting proteins have been characterized by NMR spectroscopy mostly by using chemical shift perturbations and cross ...

Springer Verlag2010

LiZnNb4O11.5: A novel oxygen deficient compound in the Nb-rich part of the Li2O–ZnO–Nb2O5 system

Gervais Chapuis, Alla Arakcheeva, Philip Pattison

A novel lithium zinc niobium oxide LiZnNb4O11.5 (LZNO) has been found in the Nb-rich part of Li2O–ZnO–Nb2O5 system. LZNO, with an original a-PbO2 related structure, has been synthesized by the routine ceramic technique and characterized by X-ray diffractio ...

2010

Retrieving photochemically active structures by time-resolved EXAFS spectroscopy

Majed Chergui, Wojciech Gawelda, Camelia Borca, Van Thai Pham, Amal El Nahhas, Renske Marjan van der Veen, Frederico Alves Lima

Describing the nature and structure of molecular excited states is important in order to understand their chemical reactivity and role as intermediates in photochemical reactions. The recent implementation of x-ray absorption spectroscopy in the ultrafast ...

Iop Publishing Ltd, Dirac House, Temple Back, Bristol Bs1 6Be, England2009

Functional analysis and structural modeling of human APOBEC3G reveal the role of evolutionarily conserved elements in the inhibition of human immunodeficiency virus type 1 infection and Alu transposition

Didier Trono, Priscilla Turelli, Bastien Mangeat, Olivier Michielin

Retroelements are important evolutionary forces but can be deleterious if left uncontrolled. Members of the human APOBEC3 family of cytidine deaminases can inhibit a wide range of endogenous, as well as exogenous, retroelements. These enzymes are structura ...

2009

Structural determination of photochemically active diplatinum molecule by time-resolved EXAFS spectroscopy

Majed Chergui, Van Thai Pham, Amal El Nahhas, Renske Marjan van der Veen, Frederico Alves Lima

Metallica: A large contraction of the PtPt bond in the triplet excited state of the photoreactive [Pt2(P2O5H2)4]4- ion is determined by time-resolved X-ray absorption spectroscopy (see picture). The strengthening of the PtPt interaction is accompanied by a ...

2009

Structure and stability of the Si(331)-(12x1) surface reconstruction investigated with first-principles density functional theory

Corsin Battaglia

We recently proposed a structural model for the Si!331"-!12!1" surface reconstruction containing silicon pentamers and adatoms as elementary structural building blocks. Using first-principles density functional theory we here investigate the stability of a ...

2009

Crystal Structures of Limulus SAP-Like Pentraxin Reveal Two Molecular Aggregations

Henning Paul-Julius Stahlberg

The serum-amyloid-P-component-like pentraxin from Limulus polyphemus, a recently discovered pentraxin species and important effector protein of the hemolymph immune system, displays two distinct doubly stacked cyclic molecular aggregations, heptameric and ...

Elsevier BV2009

Non-180° domains in LiTaO3 thin films deposited by metal organic chemical vapor deposition

Nava Setter

Epitaxial lithium tantalate (LiTaO3) thin films were grown on the hexagonal plane of sapphire substrates by metal organic chemical vapor deposition. Two crystallographic variants, related to each other by 180° rotation around the c axis, as well as non-180 ...

2009

Dynamics and Thermodynamics of a Novel Phase of NaAlH4

Nicola Marzari

We characterize a novel orthorhombic phase (gamma) of NaAlH4, discovered using first-principles molecular dynamics, and discuss its relevance to the dehydrogenation mechanism. This phase is close in energy to the known low-temperature structure and becomes ...

2009

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