Concept
Male infertility
Related publications (36)
An atypical mitogen-activated protein kinase controls cytokinesis and flagellar motility during male gamete formation in a malaria parasite
The transmission of malaria parasites to the mosquito depends critically on the rapid initiation of sexual reproduction in response to triggers from the mosquito midgut environment. We here identify an essential function for an atypical mitogen-activated p ...
Wiley-Blackwell2005A mitogen-activated protein kinase regulates male gametogenesis and transmission of the malaria parasite Plasmodium berghei
Differentiation of malaria parasites into sexual forms (gametocytes) in the vertebrate host and their subsequent development into gametes in the mosquito vector are crucial steps in the completion of the parasite's life cycle and transmission of the diseas ...
Nature Publishing Group2005Ligand-dependent contribution of RXRbeta to cholesterol homeostasis in Sertoli cells
We show that mice expressing retinoid X receptor beta (RXRbeta) impaired in its transcriptional activation function AF-2 (Rxrb(af20) mutation) do not display the spermatid release defects observed in RXRbeta-null mutants, indicating that the role of RXRbet ...
2004Male accessory sex organ morphogenesis is altered by loss of function of Hoxd-13
The role of the Hox gene Hoxd-13 in postnatal morphogenesis of the male accessory sex organs was examined by correlating the distribution and temporal regulation of expression in the accessory sex organs of postnatal mice with morphologic abnormalities of ...
1997Modulators of ob gene and screening methods therefor
This invention relates to the isolation and cloning of the promoter and other control regions of a human ob gene. It provides a method for identifying and screening for agents useful for the treatment of diseases and pathological conditions affected by the ...
1996Effects of sex steroids on hepatic and lipoprotein lipase activity and mRNA in the rat
In humans, sex steroids have been implicated in the regulation of hepatic and lipoprotein lipase activity. Therefore, the effects of orchidectomy and subsequent androgen or estrogen administration on hepatic lipase (HL) and adipose tissue and heart lipopro ...
1993