Concept

Antinuclear antibody

Related publications (88)

System and Method For In Vivo Delivery of Antibodies and Fragments Thereof

Patrick Aebischer, Maurizio Molinari, Nicolas Bouche

The present invention is directed to devices and methods for in situ delivering an antibody or a fragment thereof to a host. In particular, the invention relates to devices and methods for in situ delivering an antibody or a fragment thereof to patient suf ...

2011

Chronic delivery of antibody fragments using immunoisolated cell implants as a passive vaccination tool

Rolf Gruetter, Maria del Carmen Sandi Perez, Patrick Aebischer, Maurizio Molinari, Maria Isabel Cordero Campana, Jean-Charles Bensadoun, Nicolas Bouche, Veronica Setola, Osiris Marroquin Belaunzaran

BACKGROUND: Monoclonal antibodies and antibody fragments are powerful biotherapeutics for various debilitating diseases. However, high production costs, functional limitations such as inadequate pharmacokinetics and tissue accessibility are the current pri ...

Public Library of Science2011

Mutation of the BAFF furin cleavage site impairs B-cell homeostasis and antibody responses

Friedrich Beermann

B-cell-activating factor of the TNF family (BAFF)/BLyS contributes to B-cell homeostasis and function in the periphery. BAFF is expressed as a membrane-bound protein or released by proteolytic cleavage, but the functional importance of this processing even ...

Wiley-Blackwell2011

Characterization of glycoprotein E C-End of West Nile virus and evaluation of its interaction force with alpha V beta 3 integrin as putative cellular receptor

Giovanni Dietler

Recombinant polypeptide containing the 260-466 amino acid sequence of West Nile virus (WNV) strain LEIV-Vlg99-27889-human glycoprotein E (gpE, E260-466) was constructed. Immunochemical similarity between the E260-466 and gpE of WNV was proven by enzyme imm ...

2010

Bioconjugation of barium titanate nanocrystals with immunoglobulin G antibody for second harmonic radiation imaging probes

Demetri Psaltis, Ye Pu, Rachel Grange, Chia-Lung Hsieh

The second harmonic generation (SHG) active nanocrystals have been demonstrated as attractive imaging probes in nonlinear microscopy due to their coherent, non-bleaching and non-blinking signals with a broad flexibility in the choice of excitation waveleng ...

Elsevier2010

Monolithic Silicon Chip for Immunofluorescence Detection on Single Magnetic Beads

Edoardo Charbon, Martinus Gijs, Ulrike Lehmann, Caroline Vandevyver, Emile Dupont

While fluorescence detection is widely used for bioassays owing to its high sensitivity, a complete fluorescent microscopy setup, comprised of a light source, optical filters, a microscope body, and a camera, still is bulky equipment, compromising its use ...

2010

Trace-Level Detection of Atrazine Using Immuno-Chemiluminescence: Dipstick and Automated Flow Injection Analyses Formats

Ravindranathan Thampi

A sensitive chemiluminescence (CL)-based immunoassay technique based on both dipstick and flow injection analytical formats is reported for the detection of atrazine. In the dipstick-based immunoassay technique, antibody (anti-atrazine) was first immobiliz ...

2010

Magnetic beads retention device for sandwich immunoassay: comparison of off-chip and on-chip antibody incubation

Martinus Gijs, Caroline Vandevyver, Frédéric Lacharme

We use magnetic microbeads, which are magnetically self-assembled in chains in a microfluidic chip, as reaction substrates to implement two different sandwich immunoassay protocols for the detection of mouse monoclonal target antibodies. The magnetic chain ...

Springer-Verlag2009

HLA-C cell surface expression and control of HIV/AIDS correlate with a variant upstream of HLA-C

Jacques Fellay, Amalio Telenti

A variant 35 kb upstream of the HLA-C gene (-35C/T) was previously shown to associate with HLA-C mRNA expression level and steady-state plasma HIV RNA levels. We genotyped this variant in 1,698 patients of European ancestry with HIV. Individuals with known ...

2009

Bioprocédés intégrés et innovateurs pour la dépollution des eaux

Christof Holliger

L’immense diversité métabolique du monde des micro-organismes est la clé pour la dépollution biologique des eaux, des sols, des nappes phréatiques et de l’air. Les bioprocédés appliqués se classent principalement parmi les technologies « end-of-pipe » qui ...

2009

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