Publications related to Transcription factor

The Eukaryotic Promoter Database: expansion of EPDnew and new promoter analysis tools

Giovanna Ambrosini, Philipp Bucher, René Dreos, Rouayda Cavin Perier

We present an update of EPDNew (http://epd. vital-it. ch), a recently introduced new part of the Eukaryotic Promoter Database (EPD) which has been described in more detail in a previous NAR Database Issue. EPD is an old database of experimentally character ...

Oxford University Press2015

Upstream Binding of Idling RNA Polymerase Modulates Transcription Initiation from a Nearby Promoter

Giovanni Dietler, Aleksandre Japaridze

The bacterial gene regulatory regions often demonstrate distinctly organized arrays of RNA polymerase binding sites of illdefined function. Previously we observed a module of closely spaced polymerase binding sites upstream of the canonical promoter of the ...

American Society for Biochemistry and Molecular Biology2015

Structure of silent transcription intervals and noise characteristics of mammalian genes

Felix Naef, Benjamin Zoller, Damien Lionel Nicolas

Mammalian transcription occurs stochastically in short bursts interspersed by silent intervals showing a refractory period. However, the underlying processes and consequences on fluctuations in gene products are poorly understood. Here, we use single allel ...

Nature / European Molecular Biology Organization2015

Visualizing the HoxD Gene Cluster at the Nanoscale Level

Denis Duboule, Suliana Manley, Aleksandr Benke, Pierre Raymond Fabre

Transcription of HoxD cluster genes in limbs is coordinated by two topologically associating domains (TADs), neighboring the cluster and containing various enhancers. Here, we use a combination of microscopy approaches and chromosome conformation capture t ...

2015

Nucleosome Stability Distinguishes Two Different Promoter Types at All Protein-Coding Genes in Yeast

Jacques Rougemont, Philippe Jacquet

Previous studies indicate that eukaryotic promoters display a stereotypical chromatin landscape characterized by a well-positioned +1 nucleosome near the transcription start site and an upstream 1 nucleosome that together demarcate a nucleosome-free (or -d ...

Elsevier2015

TRIM33 switches off Ifnb1 gene transcription during the late phase of macrophage activation

Michele De Palma, Mario Leonardo Squadrito

Despite its importance during viral or bacterial infections, transcriptional regulation of the interferon-beta gene (Ifnb1) in activated macrophages is only partially understood. Here we report that TRIM33 deficiency results in high, sustained expression o ...

Nature Publishing Group2015

The genetics of social hierarchies

Maria del Carmen Sandi Perez, Michael van der Kooij

The organization of individuals in social hierarchies is ubiquitous in social species. Although the evolution of dominance at the population level is constrained by its interactive character, selective breeding shows that dominance and subordination can be ...

2015

Genetic, molecular and physiological basis of variation in Drosophila gut immunocompetence

Bruno Lemaitre, Bart Deplancke, Andreas Massouras, Maroun Bou Sleiman, Dani Osman

Gut immunocompetence involves immune, stress and regenerative processes. To investigate the determinants underlying inter-individual variation in gut immunocompetence, we perform enteric infection of 140 Drosophila lines with the entomopathogenic bacterium ...

Nature Publishing Group2015

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Transcription factor

The Eukaryotic Promoter Database: expansion of EPDnew and new promoter analysis tools

Upstream Binding of Idling RNA Polymerase Modulates Transcription Initiation from a Nearby Promoter

Structure of silent transcription intervals and noise characteristics of mammalian genes

Visualizing the HoxD Gene Cluster at the Nanoscale Level

Nucleosome Stability Distinguishes Two Different Promoter Types at All Protein-Coding Genes in Yeast

TRIM33 switches off Ifnb1 gene transcription during the late phase of macrophage activation

Chromatin organization, transcription factor dynamics and gene expression in higher eukaryotes with superresolution imaging and single molecule tracking

The genetics of social hierarchies

Elucidating the role of Hmx1 during mouse development

Genetic, molecular and physiological basis of variation in Drosophila gut immunocompetence

Graph Chatbot

Chat with Graph Search

Upstream Binding of Idling RNA Polymerase Modulates Transcription Initiation from a Nearby Promoter

Structure of silent transcription intervals and noise characteristics of mammalian genes

The Eukaryotic Promoter Database: expansion of EPDnew and new promoter analysis tools

Visualizing the HoxD Gene Cluster at the Nanoscale Level

Nucleosome Stability Distinguishes Two Different Promoter Types at All Protein-Coding Genes in Yeast

TRIM33 switches off Ifnb1 gene transcription during the late phase of macrophage activation

Chromatin organization, transcription factor dynamics and gene expression in higher eukaryotes with superresolution imaging and single molecule tracking

The genetics of social hierarchies

Elucidating the role of Hmx1 during mouse development

Genetic, molecular and physiological basis of variation in Drosophila gut immunocompetence