Spatial analysis is any of the formal techniques which studies entities using their topological, geometric, or geographic properties. Spatial analysis includes a variety of techniques using different analytic approaches, especially spatial statistics. It may be applied in fields as diverse as astronomy, with its studies of the placement of galaxies in the cosmos, or to chip fabrication engineering, with its use of "place and route" algorithms to build complex wiring structures. In a more restricted sense, spatial analysis is geospatial analysis, the technique applied to structures at the human scale, most notably in the analysis of geographic data. It may also be applied to genomics, as in transcriptomics data. Complex issues arise in spatial analysis, many of which are neither clearly defined nor completely resolved, but form the basis for current research. The most fundamental of these is the problem of defining the spatial location of the entities being studied. Classification of the techniques of spatial analysis is difficult because of the large number of different fields of research involved, the different fundamental approaches which can be chosen, and the many forms the data can take. Spatial analysis began with early attempts at cartography and surveying. Land surveying goes back to at least 1,400 B.C in Egypt: the dimensions of taxable land plots were measured with measuring ropes and plumb bobs. Many fields have contributed to its rise in modern form. Biology contributed through botanical studies of global plant distributions and local plant locations, ethological studies of animal movement, landscape ecological studies of vegetation blocks, ecological studies of spatial population dynamics, and the study of biogeography. Epidemiology contributed with early work on disease mapping, notably John Snow's work of mapping an outbreak of cholera, with research on mapping the spread of disease and with location studies for health care delivery. Statistics has contributed greatly through work in spatial statistics.

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