Agency for Toxic Substances and Disease Registry

The Agency for Toxic Substances and Disease Registry (ATSDR) is a federal public health agency within the United States Department of Health and Human Services. The agency focuses on minimizing human health risks associated with exposure to hazardous substances. It works closely with other federal, state, and local agencies; tribal governments; local communities; and healthcare providers. Its mission is to "Serve the public through responsive public health actions to promote healthy and safe environments and prevent harmful exposures." ATSDR was created as an advisory, nonregulatory agency by the Superfund legislation and was formally organized in 1985. Although ATSDR is an independent operating agency within the Department of Health and Human Services, the Centers for Disease Control and Prevention (CDC) performs many of its administrative functions. The CDC director also serves as the ATSDR administrator, and ATSDR has a joint Office of the Director with the National Center for Environmental Health (NCEH). The ATSDR headquarters are located in Atlanta, Georgia, at the CDC Chamblee campus. In fiscal year 2010, ATSDR had an operating budget of $76.8 million and had roughly 300 full-time employees (not including contractors). The ATSDR is formally and administratively overseen by the Director of the Centers for Disease Control and Prevention (CDC), currently Dr. Mandy Cohen since July 10, 2023 Direction is provided by ATSDR's Director, currently Dr. Patrick N. Breysse, who ranks below the Administrator, and ATSDR's Associate Director, currently Dr. Christopher M. Reh. ATSDR is an agency within the US Department of Health and Human Services concerned with the effects of hazardous substances on human health. ATSDR is charged with assessing the presence and nature of health hazards at specific Superfund sites, as well as helping prevent or reduce further exposure and the illnesses that can result from such exposures. ATSDR is an oversight agency created to ensure that public health protection and environmental regulation work hand in hand.

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Love Canal

Love Canal is a neighborhood in Niagara Falls, New York, United States, infamous as the location of a landfill that became the site of an enormous environmental disaster in the 1970s. Decades of dumping toxic chemicals harmed the health of hundreds of residents; the area was cleaned up over the course of 21 years in a Superfund operation. In 1890, Love Canal was created as a model planned community, but was only partially developed. In the 1920s, the canal became a dump site for municipal refuse for the city of Niagara Falls.

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Toxicity is the degree to which a chemical substance or a particular mixture of substances can damage an organism. Toxicity can refer to the effect on a whole organism, such as an animal, bacterium, or plant, as well as the effect on a substructure of the organism, such as a cell (cytotoxicity) or an organ such as the liver (hepatotoxicity). By extension, the word may be metaphorically used to describe toxic effects on larger and more complex groups, such as the family unit or society at large.

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