Publications related to Interleukin 13

Thymic stromal lymphopoietin plays divergent roles in murine models of atopic and nonatopic airway inflammation

Nicola Harris, Benjamin John Marsland, Ilaria Mosconi

BackgroundThymic stromal lymphopoietin (TSLP) is a cytokine primarily produced by epithelial cells, which has been shown to be a potent inducer of T-helper 2 (Th2)-type responses. However, TSLP has pleiotropic effects upon immune cells, and although extens ...

Wiley-Blackwell2014

Antibodies Trap Tissue Migrating Helminth Larvae and Prevent Tissue Damage by Driving IL-4Rα-Independent Alternative Differentiation of Macrophages

Arne Seitz, Romain Guiet, Nicola Harris, Alessandra Piersigilli, Beatrice Volpe, Julia Esser-von Bieren, Ilaria Mosconi, Fei Chen

Approximately one-third of the world's population suffers from chronic helminth infections with no effective vaccines currently available. Antibodies and alternatively activated macrophages (AAM) form crucial components of protective immunity against chall ...

Public Library of Science2013

IL-1β Suppresses Innate IL-25 and IL-33 Production and Maintains Helminth Chronicity

Nicola Harris, Benjamin John Marsland, Mario Michael Zaiss, Ilaria Mosconi, Nadine Guenat

Approximately 2 billion people currently suffer from intestinal helminth infections, which are typically chronic in nature and result in growth retardation, vitamin A deficiency, anemia and poor cognitive function. Such chronicity results from co-evolution ...

Public Library Science2013

TSLP promotes influenza-specific CD8+ T-cell responses by augmenting local inflammatory dendritic cell function

Nicola Harris, Benjamin John Marsland

Thymic stromal lymphopoietin (TSLP) is a mucosal tissue-associated cytokine that has been widely studied in the context of T helper type 2 (Th2)-driven inflammatory disorders. Although TSLP is also produced upon viral infection in vitro, the role of TSLP i ...

Nature Publishing Group2013

NutriChip: Nutrition Analysis meets Microfluidics

Martinus Gijs, Sandro Carrara, Paolo Silacci, Gözen Köklü, Julien Michel Ghaye, Hamideh Jafarpoorchekab, Christine Ruffert, Guy Vergères

This focus article introduces the concept of NutriChip, an integrated microfluidic platform for investigating the potential of the immuno-modulatory function of dairy food. The core component of the NutriChip is a miniaturized artificial human gastrointest ...

Royal Society of Chemistry2013

Antibodies and IL-3 support helminth-induced basophil expansion

Nicola Harris, Mario Michael Zaiss, Manuel Kulagin, Tina Herbst

Basophils are powerful mediators of Th2 immunity and are present in increased numbers during allergic inflammation and helminth infection. Despite their ability to potentiate Th2 immunity the mechanisms regulating basophil development remain largely unknow ...

Natl Acad Sciences2012

Redundant Notch1 and Notch2 Signaling Is Necessary for IFNγ Secretion by T Helper 1 Cells During Infection with Leishmania major

Freddy Radtke, Ute Koch, Floriane Auderset

The protective immune response to intracellular parasites involves in most cases the differentiation of IFNγ-secreting CD4(+) T helper (Th) 1 cells. Notch receptors regulate cell differentiation during development but their implication in the polarization ...

2012

Dendritic cell activation and T cell priming with adjuvant- and antigen-loaded oxidation-sensitive polymersomes

Jeffrey Alan Hubbell, Melody Swartz, Armando Stano

While current subunit vaccines successfully induce humoral immune responses, a need exists for vaccine strategies to elicit strong cell-mediated immunity to address diseases such as cancer and chronic viral infection. Polymersomes are stable vesicles compo ...

2012

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Interleukin 13

Thymic stromal lymphopoietin plays divergent roles in murine models of atopic and nonatopic airway inflammation

Antibodies Trap Tissue Migrating Helminth Larvae and Prevent Tissue Damage by Driving IL-4Rα-Independent Alternative Differentiation of Macrophages

IL-1β Suppresses Innate IL-25 and IL-33 Production and Maintains Helminth Chronicity

TSLP promotes influenza-specific CD8+ T-cell responses by augmenting local inflammatory dendritic cell function

NutriChip: Nutrition Analysis meets Microfluidics

Partners in crime: VEGF and IL-4 conscript tumour-promoting macrophages

Antibodies and IL-3 support helminth-induced basophil expansion

Transcription factor ROR alpha is critical for nuocyte development

Redundant Notch1 and Notch2 Signaling Is Necessary for IFNγ Secretion by T Helper 1 Cells During Infection with Leishmania major

Dendritic cell activation and T cell priming with adjuvant- and antigen-loaded oxidation-sensitive polymersomes

Graph Chatbot

Chat with Graph Search

IL-1β Suppresses Innate IL-25 and IL-33 Production and Maintains Helminth Chronicity

TSLP promotes influenza-specific CD8+ T-cell responses by augmenting local inflammatory dendritic cell function

Antibodies and IL-3 support helminth-induced basophil expansion

Transcription factor ROR alpha is critical for nuocyte development

Dendritic cell activation and T cell priming with adjuvant- and antigen-loaded oxidation-sensitive polymersomes

Antibodies Trap Tissue Migrating Helminth Larvae and Prevent Tissue Damage by Driving IL-4Rα-Independent Alternative Differentiation of Macrophages

NutriChip: Nutrition Analysis meets Microfluidics

Thymic stromal lymphopoietin plays divergent roles in murine models of atopic and nonatopic airway inflammation

Partners in crime: VEGF and IL-4 conscript tumour-promoting macrophages

Redundant Notch1 and Notch2 Signaling Is Necessary for IFNγ Secretion by T Helper 1 Cells During Infection with Leishmania major