Concept
Gonadotropin-releasing hormone agonist
Related publications (16)
Extended gate field-effect-transistor for sensing cortisol stress hormone
Mihai Adrian Ionescu, Junrui Zhang, Sadegh Kamaei Bahmaei, Hoël Maxime Guérin, Luca Capua, Shokoofeh Sheibani, Sayedeh Shirin Afyouni Akbari
Cortisol is a hormone released in response to stress and is a major glucocorticoid produced by adrenal glands. Here, we report a wearable sensory electronic chip using label-free detection, based on a platinum/graphene aptamer extended gate field effect tr ...
SPRINGERNATURE2021Design, Synthesis and in vitro Controlled Release of New Adamantanodiarylketone Antimycobacterials
In the present investigation, the synthesis, the biology and the development of matrix tablet formulations for the in vitro controlled release of new adamantane diarylketone antimycobacterial derivatives, is presented. In the skeleton of the new compounds, ...
WILEY-V C H VERLAG GMBH2019A high resolution LC-MS targeted method for the concomitant analysis of 11 contraceptive progestins and 4 steroids
Cathrin Brisken, Jonathan Paz Montoya, Marc Moniatte, Fabio De Martino, Marie Shamseddin, Csaba Ferenc László, Alexandre Béguin
In the context of hormonal contraception and hormone replacement therapy (HRT), many women are exposed to exogenous hormones. Current use of hormonal contraception with combined ethinyl estradiol and different progestins bestows a breast cancer relative ri ...
2019In vitro Controlled Release from Solid Pharmaceutical Formulations of two new Adamantane Aminoethers with Antitubercular Activity (I).
The aim of the present investigation was to develop matrix tablet formulations for the in vitro controlled release of 2 new tuberculocidal adamantane aminoethers (compounds I and II), congeneric to the adamantane derivative SQ109 , which is in final clinic ...
Georg Thieme Verlag Kg2017Ovary-specific depletion of the nuclear receptor Nr5a2 compromises expansion of the cumulus oophorus but not fertilization by intracytoplasmic sperm injection
The orphan nuclear receptor, liver receptor homolog-1 (aka Nuclear receptor subfamily 5, Group A, Member 2 (Nr5a2)), is widely expressed in mammalian tissues, and its ovarian expression is restricted to granulosa cells of activated follicles. We employed t ...
Society for the Study of Reproduction2017Murine ovarian follicle culture in PEG-hydrogel: Effects of mechanical properties and the hormones FSH and LH on development
Jeffrey Alan Hubbell, Seung Tae Lee, Jong Eun Ihm
The development of an in vitro culture system, comparable to the in vivo environment in terms of effects on oocyte growth and development, could provide a valuable experimental tool for studying the mechanisms governing oocyte development as well as practi ...
Polymer Soc Korea2015Effects of clofibric acid alone and in combination with 17 beta-estradiol on mRNA abundance in primary hepatocytes isolated from rainbow trout
Clofibric acid (CA) is the active substance of lipid lowering drugs. It is resistant to degradation, polar in nature, and has been found ubiquitously in the aquatic environment. Though CA is classified as a peroxisomal proliferator in rodents and is consid ...
Pergamon-Elsevier Science Ltd2014The Orphan Nuclear Receptor Nr5a2 Is Essential for Luteinization in the Female Mouse Ovary
In the ovary, the follicular granulosa cells express the nuclear receptor Nr5a2 (nuclear receptor subfamily 5 group A member 2), also known as liver receptor homolog-1, and after ovulation, Nr5a2 expression persists in the corpus luteum. Previous studies d ...
Endocrine Soc2014NR5A2 Regulates Lhb and Fshb Transcription in Gonadotrope-Like Cells In Vitro, but Is Dispensable for Gonadotropin Synthesis and Fertility In Vivo
Johan Auwerx, Kristina Schoonjans, Yiping Wang, Xin Zhou, Vikas Kumar
Successful mammalian reproduction depends on proper synthesis of the pituitary-derived glycoprotein hormones, luteinizing hormone (LH) and follicle-stimulating hormone (FSH). Several transcription factors cooperate to activate cell-specific and hormone-reg ...
Public Library of Science2013Probing Odorant-Mediated Receptor Activation
Molecular interactions of odorants with their olfactory receptors (ORs) are of central importance for the mammalian olfactory system to detect and discriminate a large variety of odors with a limited set of receptors. How a particular OR binds and distingu ...
EPFL2012