Publications related to Detoxification

Probiotics and gut microbiome-Prospects and challenges in remediating heavy metal toxicity

The gut microbiome, often referred to as "super organ", comprises up to a hundred trillion microorganisms, and the species diversity may vary from person to person. They perform a decisive role in diverse biological functions related to metabolism, immunit ...

ELSEVIER2021

Augmented mitochondrial energy metabolism is an early response to chronic glucose stress in human pancreatic beta cells

Loïc Dayon, Andreas Wiederkehr, Sofia Moco, Isabelle Chareyron

Aims/hypothesis In islets from individuals with type 2 diabetes and in islets exposed to chronic elevated glucose, mitochondrial energy metabolism is impaired. Here, we studied early metabolic changes and mitochondrial adaptations in human beta cells durin ...

2020

Disruption of redox homeostasis by enzymatic activation of a triakylphosphine probe in mitochondria

Pablo Rivera Fuentes, Jade Noémie Nam Nguyen

Redox homeostasis is essential for cell function and its disruption is assocd. with cancer, metabolic and neurodegenerative diseases. Redox balance is largely regulated by the relative concns. of reduced and oxidized glutathione. In eukaryotes, this ratio ...

2019

MicroRNA-382 silencing induces a mitonuclear protein imbalance and activates the mitochondrial unfolded protein response in muscle cells

Johan Auwerx, Pénélope Andreux, Xu Wang, Norman Lionel Moullan

Proper mitochondrial function plays a central role in cellular metabolism. Various diseases as well as aging are associated with diminished mitochondrial function. Previously, we identified 19 miRNAs putatively involved in the regulation of mitochondrial m ...

WILEY2019

Non-invasive diagnosis and metabolic consequences of congenital portosystemic shunts in C57BL/6 J mice

Hongxia Lei, Ana Francisca Leal Silva Soares

This study demonstrates the suitability of magnetic resonance imaging (MRI) and magnetic resonance angiography (MRA) for the imaging of congenital portosystemic shunts (PSS) in mice, a vascular abnormality in which mesenteric blood bypasses the liver and i ...

2018

Toward fully characterized knowledge gaps in metabolic networks: discovery of missing biochemistry in Escherichia coli

Vassily Hatzimanikatis, Meriç Ataman, Noushin Hadadi

Advances in medicine and biotechnology rely on the further understanding of biological processes. Despite the technological advances and increasing available types and amounts of omics data, significant biochemical knowledge gaps remain uncharacterised. We ...

2017

Facing The Unknown: Suggesting Alternative Novel Biochemistry in Escherichia coli and Saccharomyces cerevisiae

Vassily Hatzimanikatis, Meriç Ataman, Noushin Hadadi

While advances in genome sequencing have greatly facilitated the inference of metabolic networks, the presence of unknown biochemistry in the organisms still challenges the analysis and understanding of metabolism. Even for one of the most known organism l ...

2017

Diurnal Oscillations in Liver Mass and Cell Size Accompany Ribosome Assembly Cycles

Frédéric Bruno Martin Gachon, Daniel Alain Dominique Marie Mauvoisin, Jingkui Wang

The liver plays a pivotal role in metabolism and xenobiotic detoxification, processes that must be particularly efficient when animals are active and feed. A major question is how the liver adapts to these diurnal changes in physiology. Here, we show that, ...

Cell Press2017

Chat with Graph Search

Ask any question about EPFL courses, lectures, exercises, research, news, etc. or try the example questions below.

DISCLAIMER: The Graph Chatbot is not programmed to provide explicit or categorical answers to your questions. Rather, it transforms your questions into API requests that are distributed across the various IT services officially administered by EPFL. Its purpose is solely to collect and recommend relevant references to content that you can explore to help you answer your questions.

Detoxification

Dissecting the role of the asparagine synthesis in acute liver injury

Probiotics and gut microbiome-Prospects and challenges in remediating heavy metal toxicity

Methylation of arsenic by single-species and soil-derived microbial cultures

Augmented mitochondrial energy metabolism is an early response to chronic glucose stress in human pancreatic beta cells

Disruption of redox homeostasis by enzymatic activation of a triakylphosphine probe in mitochondria

MicroRNA-382 silencing induces a mitonuclear protein imbalance and activates the mitochondrial unfolded protein response in muscle cells

Non-invasive diagnosis and metabolic consequences of congenital portosystemic shunts in C57BL/6 J mice

Toward fully characterized knowledge gaps in metabolic networks: discovery of missing biochemistry in Escherichia coli

Facing The Unknown: Suggesting Alternative Novel Biochemistry in Escherichia coli and Saccharomyces cerevisiae

Diurnal Oscillations in Liver Mass and Cell Size Accompany Ribosome Assembly Cycles

Graph Chatbot

Chat with Graph Search

Augmented mitochondrial energy metabolism is an early response to chronic glucose stress in human pancreatic beta cells

Dissecting the role of the asparagine synthesis in acute liver injury

Non-invasive diagnosis and metabolic consequences of congenital portosystemic shunts in C57BL/6 J mice

Facing The Unknown: Suggesting Alternative Novel Biochemistry in Escherichia coli and Saccharomyces cerevisiae

Methylation of arsenic by single-species and soil-derived microbial cultures

Diurnal Oscillations in Liver Mass and Cell Size Accompany Ribosome Assembly Cycles

MicroRNA-382 silencing induces a mitonuclear protein imbalance and activates the mitochondrial unfolded protein response in muscle cells

Disruption of redox homeostasis by enzymatic activation of a triakylphosphine probe in mitochondria

Probiotics and gut microbiome-Prospects and challenges in remediating heavy metal toxicity

Toward fully characterized knowledge gaps in metabolic networks: discovery of missing biochemistry in Escherichia coli