May 61527 – Spanish and German troops sack Rome; many scholars consider this the end of the Renaissance. 1536 – The Siege of Cuzco commences, in which Incan forces attempt to retake the city of Cuzco from the Spanish. 1541 – King Henry VIII orders English-language Bibles be placed in every church. In 1539 the Great Bible would be provided for this purpose. 1542 – Francis Xavier reaches Old Goa, the capital of Portuguese India at the time. 1594 – The Dutch city of Coevorden held by the Spanish, falls to a Dutch and English force.
1965January 1965 February 1965 January 14 – The Prime Minister of Northern Ireland and the Taoiseach of the Republic of Ireland meet for the first time in 43 years. January 20 Lyndon B. Johnson is sworn in for a full term as President of the United States. Indonesian President Sukarno announces the withdrawal of the Indonesian government from the United Nations. January 30 – The state funeral of Sir Winston Churchill takes place in London with the largest assembly of dignitaries in the world until the 2005 funeral of Pope John Paul II.
May 1028 BC – A sunspot is observed by Han dynasty astronomers during the reign of Emperor Cheng of Han, one of the earliest dated sunspot observations in China. 1291 – Scottish nobles recognize the authority of Edward I of England pending the selection of a king. 1294 – Temür, Khagan of the Mongols, is enthroned as Emperor of the Yuan dynasty. 1497 – Amerigo Vespucci allegedly leaves Cádiz for his first voyage to the New World. 1503 – Christopher Columbus visits the Cayman Islands and names them Las Tortugas after the numerous turtles there.
February 25138 – Roman emperor Hadrian adopts Antoninus Pius as his son, effectively making him his successor. 628 – Khosrow II, the last great Shah of the Sasanian Empire (Iran), is overthrown by his son Kavadh II. 1336 – Four thousand defenders of Pilenai commit mass suicide rather than be taken captive by the Teutonic Knights. 1705 – George Frideric Handel's opera Nero premiered in Hamburg. 1836 – Samuel Colt is granted a United States patent for his revolver firearm.
April 201303 – The Sapienza University of Rome is instituted by a bull of Pope Boniface VIII. 1653 – Oliver Cromwell dissolves England's Rump Parliament. 1657 – English Admiral Robert Blake destroys a Spanish silver fleet, under heavy fire from the shore, at the Battle of Santa Cruz de Tenerife. 1657 – Freedom of religion is granted to the Jews of New Amsterdam (later New York City). 1752 – Start of Konbaung–Hanthawaddy War, a new phase in the Burmese Civil War (1740–57).
April 261336 – Francesco Petrarca (Petrarch) ascends Mont Ventoux. 1478 – The Pazzi family attack on Lorenzo de' Medici in order to displace the ruiling Medici family kills his brother Giuliano during High Mass in Florence Cathedral. 1564 – Playwright William Shakespeare is baptized in Stratford-upon-Avon, Warwickshire, England (date of birth is unknown). 1607 – The Virginia Company colonists make landfall at Cape Henry. 1721 – A massive earthquake devastates the Iranian city of Tabriz.
April 221500 – Portuguese navigator Pedro Álvares Cabral lands in Brazil. 1519 – Spanish conquistador Hernán Cortés establishes a settlement at Veracruz, Mexico. 1529 – Treaty of Zaragoza divides the eastern hemisphere between Spain and Portugal along a line 297.5 leagues () east of the Moluccas. 1809 – The second day of the Battle of Eckmühl: The Austrian army is defeated by the First French Empire army led by Napoleon and driven over the Danube in Regensburg.
September 2338 – Drusilla, Caligula's sister who died in June, with whom the emperor is said to have an incestuous relationship, is deified. 1122 – Pope Callixtus II and Holy Roman Emperor Henry V agree to the Concordat of Worms to put an end to the Investiture Controversy. 1338 – The Battle of Arnemuiden, in which a French force defeats the English, is the first naval battle of the Hundred Years' War and the first naval battle in which gunpowder artillery is used.
June 264 – Augustus adopts Tiberius. 221 – Roman emperor Elagabalus adopts his cousin Alexander Severus as his heir and receives the title of Caesar. 363 – Roman emperor Julian is killed during the retreat from the Sasanian Empire. 684 – Pope Benedict II is the last pope to require confirmation by the Byzantine emperor before taking office. 699 – En no Ozuno, a Japanese mystic and apothecary who will later be regarded as the founder of a folk religion Shugendō, is banished to Izu Ōshima.
March 1509 BC – Publius Valerius Publicola celebrates the first triumph of the Roman Republic after his victory over the deposed king Lucius Tarquinius Superbus at the Battle of Silva Arsia. 293 – Emperor Diocletian and Maximian appoint Constantius Chlorus and Galerius as Caesars. This is considered the beginning of the Tetrarchy, known as the Quattuor Principes Mundi ("Four Rulers of the World"). 350 – Vetranio proclaims himself Caesar after being encouraged to do so by Constantina, sister of Constantius II.