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Blue Brain Project

Related publications (231)

An optimized protocol for assessing changes in mouse whole-brain activity using opto-fMRI

Functional magnetic resonance imaging (fMRI) in mouse brain, paired with spatially and temporally defined manipulations, offers a powerful tool to causally explain the effect of specific neuronal activity on brain network dynamics. Here, we present an opti ...

ELSEVIER2022

The neocortical column as a universal template for perception and world-model learning

Mackenzie Mathis

Mackenzie Mathis highlights an essay by Vernon Mountcastle that shaped our understanding of the organization and function of the neocortex. ...

NATURE PORTFOLIO2022

Through-Plane Super-Resolution With Autoencoders in Diffusion Magnetic Resonance Imaging of the Developing Human Brain

Meritxell Bach Cuadra, Erick Jorge Canales Rodriguez, Gabriel Girard, Hamza Kebiri

Fetal brain diffusion magnetic resonance images (MRI) are often acquired with a lower through-plane than in-plane resolution. This anisotropy is often overcome by classical upsampling methods such as linear or cubic interpolation. In this work, we employ a ...

FRONTIERS MEDIA SA2022

Investigating cognitive ability using action-based models of structural brain networks

Enrico Amico

Recent developments in network neuroscience have highlighted the importance of developing techniques for analysing and modelling brain networks. A particularly powerful approach for studying complex neural systems is to formulate generative models that use ...

OXFORD UNIV PRESS2022

The Neuron Phenotype Ontology: A FAIR Approach to Proposing and Classifying Neuronal Types

Sean Lewis Hill, Mohameth François Sy

The challenge of defining and cataloging the building blocks of the brain requires a standardized approach to naming neurons and organizing knowledge about their properties. The US Brain Initiative Cell Census Network, Human Cell Atlas, Blue Brain Project, ...

HUMANA PRESS INC2022

A computational modeling approach to study the neuromechanics of terrestrial locomotion

Shravan Tata Ramalingasetty

The main theme of my thesis will be to use neuro-muscular modeling techniques to study locomotion of terrestrial mammals. Locomotion is the ability of animals to interact with the environment to propel themselves in space. It involves co-ordination and pre ...

EPFL2022

On the Spatial Distribution of Temporal Complexity in Resting State and Task Functional MRI

Dimitri Nestor Alice Van De Ville, Maria Giulia Preti, Enrico Amico, Raphaël Pierre Liégeois, Amir Hossein Omidvarnia

Measuring the temporal complexity of functional MRI (fMRI) time series is one approach to assess how brain activity changes over time. In fact, hemodynamic response of the brain is known to exhibit critical behaviour at the edge between order and disorder. ...

MDPI2022

Large-scale brain network dynamics in very preterm children and relationship with socio-emotional outcomes: an exploratory study

Dimitri Nestor Alice Van De Ville, Vanessa Siffredi, Younes Farouj, Daniel Mourad Alfy Ramzy Tadros

Background Children born very preterm (VPT;

SPRINGERNATURE2022

A universal workflow for creation, validation and generalization of detailed neuronal models

Henry Markram, Srikanth Ramaswamy, Werner Alfons Hilda Van Geit, Alexis Arnaudon, Maria Reva, Mustafa Anil Tuncel, Darshan Mandge, Christian Andreas Rössert, Tanguy Pierre Louis Damart

Detailed single neuron modeling is widely used to study neuronal functions. While cellular and functional diversity across the mammalian cortex is vast, most of the available computational tools are dedicated to the reproduction of a small set of specific ...

2022

Pum2 and TDP-43 refine area-specific cytoarchitecture post-mitotically and modulate translation of Sox5, Bcl11b, and Rorb mRNAs in developing mouse neocortex

Nagammal Neelagandan

In the neocortex, functionally distinct areas process specific types of information. Area identity is established by morphogens and transcriptional master regulators, but downstream mechanisms driving area-specific neuronal specification remain unclear. He ...

eLIFE SCIENCES PUBL LTD2022

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