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Hypertension is a major health problem of largely unknown genetic origins. To identify new genes responsible for hypertension, genetic analysis of recombinant inbred strains of mice followed by human association studies might prove powerful and was exploit ...
Hox genes control many aspects of embryonic development in metazoans. Previous analyses of this gene family has revealed a surprising diversity in terms of gene number and organization between various animal species. In vertebrates, Hox genes are grouped i ...
The variability of terminal restriction fragment polymorphism analysis applied to complex microbial communities was assessed statistically. Recent technological improvements were implemented in the successive steps of the procedure, resulting in a standard ...
Extinction, recolonization and local adaption are common in natural spatially structured populations. Understanding their effect upon genetic variation is important for systems such as GMO management, or avoidance of drug resistance. Theoretical studies on ...
To evaluate the contribution of genetic background to phenotypic variation, we compared a large range of biochemical and metabolic parameters at different ages of four inbred mice strains, C57BL/6J, 129SvPas, C3HeB/FeJ, and Balb/cByJ. Our results demonstra ...
In several industrial case studies, we put in evidence that microsystem manufacturing costs skyrocket because of low yields. Sometimes product functionalities are badly defined ; sometimes metrology systems, in spite of their high cost, happen not to measu ...
Choosing the plant on which to lay their eggs is the last act of care that most female herbivorous insects bestow upon their offspring. These decisions play a pivotal role in insect–plant interactions, placing host preference under strong selection and ...
Good taxonomy is essential for ecological, biogeographical, and evolutionary studies of any group of organisms. Therefore, we performed detailed light- and scanning electron microscopy (SEM) investigations on the shell ultrastructure and biometric analyses ...
During the development of mammalian digits, clustered Hoxd genes are expressed following a collinear regulatory strategy, leading to both the growth of digits and their morphological identities. Because gene dosage is a key parameter in this system, we use ...
Process variation in future technologies can cause severe performance degradation since different parts of the shared Register File (RF) in VLIW processors may operate at various speeds. In this paper we present a complete approach that handles speed varia ...