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Theoretical advances and short-term experimental studies have furthered our understanding of how ecosystems respond to perturbation. However, there are few wellreplicated experimental studies that allow an assessment of long-term responses. Results from a ...
In this study, we present the development and the characterization of a generic platform for cell culture able to monitor extracellular ionic activities (K+, NH4 +) for real-time monitoring of cell-based responses, such as necrosis, apoptosis, or different ...
A fascinating property of the brain is its ability to continuously evolve and adapt to a constantly changing environment. This ability to change over time, called plasticity, is mainly implemented at the level of the connections between neurons (i.e. the s ...
Structural elements combining Ultra-High Performance Fiber Reinforced Concretes (UHPFRC)and concrete offer a high potential in view of rehabilitation and modification of existing structures. The investigation of the time-dependent behavior of composite “UH ...
The spike-triggered average voltage (STV) is an experimentally measurable quantity that is determined by both the membrane response properties and the statistics of the synaptic drive. Here, the form of the STV is modelled for neurons with three distinct t ...
The ability of motor training to encode a motor memory is reduced in older adults. Here, we tested the hypothesis that training-dependent memory encoding, an issue of relevance in neurorehabilitation, is enhanced in elder individuals by action observation ...
Memory formation has been associated with structural and functional modifications of synapses. Cell adhesion molecules are prominent modulators of synaptic plasticity. Here, we investigated the involvement of the cell adhesion molecules, NCAM, its polysial ...
Neurons in the central nervous system, and in the cortex in particular, are subject to a barrage of pulses from their presynaptic populations. These synaptic pulses are mediated by conductance changes and therefore lead to increases or decreases of the neu ...
Classical experiments on spike timing-dependent plasticity (STDP) use a protocol based on pairs of presynaptic and postsynaptic spikes repeated at a given frequency to induce synaptic potentiation or depression. Therefore, standard STDP models have express ...
During wound healing and fibrocontractive diseases fibroblasts acquire a smooth muscle cell-like phenotype by differentiating into contractile force generating myofibroblasts. We examined whether regulation of myofibroblast contraction in granulation tissu ...