Publications related to AMPA receptor

Calpain hydrolysis of alpha- and beta2-adaptins decreases clathrin-dependent endocytosis and may promote neurodegeneration

Harald Hirling, Nikita Rudinskiy

Clathrin-dependent endocytosis is mediated by a tightly regulated network of molecular interactions that provides essential protein-protein and protein-lipid binding activities. Here we report the hydrolysis of the alpha- and beta2-subunits of the tetramer ...

American Society for Biochemistry and Molecular Biology2009

Developmental regulation of the intracellular Ca2+ sensitivity of vesicle fusion and Ca2+-secretion coupling at the rat calyx of Held

Ralf Schneggenburger, Olexiy Kochubey, Yunyun Han

Developmental refinement of synaptic transmission can occur via changes in several pre- and postsynaptic factors, but it has been unknown whether the intrinsic Ca2+ sensitivity of vesicle fusion in the nerve terminal can be regulated during development. Us ...

2009

Multiquantal release underlies the distribution of synaptic efficacies in the neocortex

Henry Markram, Gilad Silberberg, Daniela Helbig

Inter-pyramidal synaptic connections are characterized by a wide range of EPSP amplitudes. Although repeatedly observed at different brain regions and across layers, little is known about the synaptic characteristics that contribute to this wide range. In ...

2009

Targeted overexpression of the parkin substrate Pael-R in the nigrostriatal system of adult rats to model Parkinson's disease

Patrick Aebischer, Bernard Schneider, Jean-Charles Bensadoun, Julien Dusonchet

Loss of function of parkin, an ubiquitin ligase, is responsible for autosomal recessive juvenile parkinsonism (AR-JP). Parkin-associated endothelin receptor-like receptor (Pael-R) was identified as an authentic substrate of parkin and is thought to accumul ...

2009

Sensory Attributes of Complex Tasting Divalent Salts Are Mediated by TRPM5 and TRPV1 Channels

Horst Vogel, Céline Riera

Complex tasting divalent salts (CTDS) are present in our daily diet, contributing to multiple poorly understood taste sensations. CTDS evoking metallic, bitter, salty, and astringent sensations include the divalent salts of iron, zinc, copper, and magnesiu ...

Society for Neuroscience2009

New designs for submillimetric press-fitting

Jacques Jacot, Fabien Bourgeois, Ludovic Charvier

Press-fitting is a very common assembly process used in many fields, especially in the watchmaking industry. It consists of introducing a shaft in a hole (also called receptor) with a certain value of tightening (or interference). However, this process is ...

Springer, 233 Spring Street, New York, Ny 10013, United States2008

Hrs and SNX3 functions in sorting and membrane invagination within multivesicular bodies

Françoise Gisou van der Goot Grunberg, Laurence Gouzi Abrami

After internalization, ubiquitinated signaling receptors are delivered to early endosomes. There, they are sorted and incorporated into the intralumenal invaginations of nascent multivesicular bodies, which function as transport intermediates to late endos ...

2008

Time-resolved luminescence microscopy of bimetallic lanthanide helicates in living cells

Jean-Claude Bünzli, Anne-Sophie Chauvin, Caroline Vandevyver, Bo Song

The cellular uptake mechanism and intracellular distribution of emissive lanthanide helicates have been elucidated by time-resolved luminescence microscopy (TRLM). The helicates are non-cytotoxic and taken up by normal (HaCat) and cancer (HeLa, MCF-7) cell ...

2008

Tag-Trigger-Consolidation: A Model of Early and Late Long-Term-Potentiation and Depression

Wulfram Gerstner, Eleni Vasilaki, Claudia Clopath, Lorric Ziegler

Changes in synaptic efficacies need to be long-lasting in order to serve as a substrate for memory. Experimentally, synaptic plasticity exhibits phases covering the induction of long-term potentiation and depression (LTP/LTD) during the early phase of syna ...

Public Library of Science2008

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AMPA receptor

Calpain hydrolysis of alpha- and beta2-adaptins decreases clathrin-dependent endocytosis and may promote neurodegeneration

Developmental regulation of the intracellular Ca2+ sensitivity of vesicle fusion and Ca2+-secretion coupling at the rat calyx of Held

Multiquantal release underlies the distribution of synaptic efficacies in the neocortex

Targeted overexpression of the parkin substrate Pael-R in the nigrostriatal system of adult rats to model Parkinson's disease

Sensory Attributes of Complex Tasting Divalent Salts Are Mediated by TRPM5 and TRPV1 Channels

New designs for submillimetric press-fitting

Co-existence of H1 and H2 histaminergic receptors in individual neurons of rat hypothalamic ventromedial nucleus (VMN)

Hrs and SNX3 functions in sorting and membrane invagination within multivesicular bodies

Time-resolved luminescence microscopy of bimetallic lanthanide helicates in living cells

Tag-Trigger-Consolidation: A Model of Early and Late Long-Term-Potentiation and Depression

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Co-existence of H1 and H2 histaminergic receptors in individual neurons of rat hypothalamic ventromedial nucleus (VMN)

Developmental regulation of the intracellular Ca2+ sensitivity of vesicle fusion and Ca2+-secretion coupling at the rat calyx of Held

Hrs and SNX3 functions in sorting and membrane invagination within multivesicular bodies

Calpain hydrolysis of alpha- and beta2-adaptins decreases clathrin-dependent endocytosis and may promote neurodegeneration

Targeted overexpression of the parkin substrate Pael-R in the nigrostriatal system of adult rats to model Parkinson's disease

Multiquantal release underlies the distribution of synaptic efficacies in the neocortex

New designs for submillimetric press-fitting

Sensory Attributes of Complex Tasting Divalent Salts Are Mediated by TRPM5 and TRPV1 Channels

Time-resolved luminescence microscopy of bimetallic lanthanide helicates in living cells

Tag-Trigger-Consolidation: A Model of Early and Late Long-Term-Potentiation and Depression