Publications related to Inner mitochondrial membrane

Oxidative stress and mitochondrial dynamics malfunction are linked in Pelizaeus-Merzbacher disease

Pelizaeus-Merzbacher disease (PMD) is a fatal hypomyelinating disorder characterized by early impairment of motor development, nystagmus, choreoathetotic movements, ataxia and progressive spasticity. PMD is caused by variations in the proteolipid protein g ...

2018

pH sensing by lipids in membranes: The fundamentals of pH-driven migration, polarization and deformations of lipid bilayer assemblies

Anne-Florence Raphaëlle Bitbol

Most biological molecules contain acido-basic groups that modulate their structure and interactions. A consequence is that pH gradients, local heterogeneities and dynamic variations are used by cells and organisms to drive or regulate specific biological f ...

Elsevier BV2018

Structural basis for regulation of human acetyl-CoA carboxylase

Henning Paul-Julius Stahlberg, Yakir Guri

Acetyl-CoA carboxylase catalyses the ATP-dependent carboxylation of acetyl-CoA, a rate-limiting step in fatty acid biosynthesis(1,2). Eukaryotic acetyl-CoA carboxylases are large, homodimeric multienzymes. Human acetyl-CoA carboxylase occurs in two isoform ...

Springer Nature2018

Biogenesis of the mitochondrial DNA inheritance machinery in the mitochondrial outer membrane of Trypanosoma brucei

Mathilde Stéphanie Willemin, André Schneider

Mitochondria cannot form de novo but require mechanisms that mediate their inheritance to daughter cells. The parasitic protozoan Trypanosoma brucei has a single mitochondrion with a single-unit genome that is physically connected across the two mitochondr ...

2017

Parkin functionally interacts with PGC-1 proportional to to preserve mitochondria and protect dopaminergic neurons

Johan Auwerx, Patrick Aebischer, Bernard Schneider, Graham Knott, Davide D'Amico, Darren Moore, Norman Lionel Moullan, Nathalie Marie Géraldine Bernard, Lu Zheng

To understand the cause of Parkinson's disease (PD), it is important to determine the functional interactions between factors linked to the disease. Parkin is associated with autosomal recessive early-onset PD, and controls the transcription of PGC-1a, a m ...

Oxford Univ Press2017

Fas cell surface death receptor controls hepatic lipid metabolism by regulating mitochondrial function

Johan Auwerx, Vera Monica Lemos Da Silva, Eija Riitta Pirinen, Matthias Alexander Sokrates Stein

Nonalcoholic fatty liver disease is one of the most prevalent metabolic disorders and it tightly associates with obesity, type 2 diabetes, and cardiovascular disease. Reduced mitochondrial lipid oxidation contributes to hepatic fatty acid accumulation. Her ...

2017

Membrane Association Landscape of Myelin Basic Protein Portrays Formation of the Myelin Major Dense Line

Henning Paul-Julius Stahlberg

Compact myelin comprises most of the dry weight of myelin, and its insulative nature is the basis for saltatory conduction of nerve impulses. The major dense line (MDL) is a 3-nm compartment between two cytoplasmic leaflets of stacked myelin membranes, mos ...

Springer Nature2017

Measurement of metabolic changes in acute doxorubicin-induced cardiotoxicity in mice using hyperpolarized [1-13C]pyruvate

Josefina Adriana Maria Bastiaansen, Hikari Ananda Infinity Yoshihara, Emine Can

Chemotherapy cocktails containing doxorubicin produce irreversible cardiotoxic side effects that may progress to heart failure, which can only be avoided through dose limitation of the chemotherapeutic agents. Increasing evidence suggest that cardiac dysfu ...

2017

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Inner mitochondrial membrane

Oxidative stress and mitochondrial dynamics malfunction are linked in Pelizaeus-Merzbacher disease

pH sensing by lipids in membranes: The fundamentals of pH-driven migration, polarization and deformations of lipid bilayer assemblies

Structural basis for regulation of human acetyl-CoA carboxylase

Microfluidic Production of Capsules-in-Capsules for Programed Release of Multiple Ingredients

Biogenesis of the mitochondrial DNA inheritance machinery in the mitochondrial outer membrane of Trypanosoma brucei

Parkin functionally interacts with PGC-1 proportional to to preserve mitochondria and protect dopaminergic neurons

Fas cell surface death receptor controls hepatic lipid metabolism by regulating mitochondrial function

Membrane Association Landscape of Myelin Basic Protein Portrays Formation of the Myelin Major Dense Line

The therapeutic role of NAD+ modulation in fatty liver disease

Measurement of metabolic changes in acute doxorubicin-induced cardiotoxicity in mice using hyperpolarized [1-13C]pyruvate

Graph Chatbot

Chat with Graph Search

pH sensing by lipids in membranes: The fundamentals of pH-driven migration, polarization and deformations of lipid bilayer assemblies

Oxidative stress and mitochondrial dynamics malfunction are linked in Pelizaeus-Merzbacher disease

Membrane Association Landscape of Myelin Basic Protein Portrays Formation of the Myelin Major Dense Line

Microfluidic Production of Capsules-in-Capsules for Programed Release of Multiple Ingredients

Measurement of metabolic changes in acute doxorubicin-induced cardiotoxicity in mice using hyperpolarized [1-13C]pyruvate

The therapeutic role of NAD+ modulation in fatty liver disease

Biogenesis of the mitochondrial DNA inheritance machinery in the mitochondrial outer membrane of Trypanosoma brucei

Fas cell surface death receptor controls hepatic lipid metabolism by regulating mitochondrial function

Structural basis for regulation of human acetyl-CoA carboxylase

Parkin functionally interacts with PGC-1 proportional to to preserve mitochondria and protect dopaminergic neurons