Concept
Cutaneous squamous-cell carcinoma
Related publications (100)
From normal cell types to malignant phenotypes
The phenotypic diversity of breast cancer has been proposed to result from different target cell types undergoing oncogenic transformation and giving rise to cancer stem cells. Global gene expression profiling revealed distinct molecular phenotypes and som ...
BioMed Central2009Asymmetric distribution of epidermal growth factor receptor directs the fate of normal and cancer keratinocytes in vitro
Cancer cells are unequal in a tumor mass and in established cultures. This is attributable to cancer stem cells with the unique ability to self-renew and to generate differentiating progeny. This ability is controlled at the level of asymmetric division by ...
2009Comparison of ALA- and ALA hexyl-ester-induced PpIX depth distribution in human skin carcinoma
Hubert van den Bergh, Georges Wagnières, Matthieu Philippe Emmanuel Zellweger, Tanja Gabrecht
Photodynamic therapy (PDT) based on the use of photoactivable porphyrins, such as protoporphyrin IX (PpIX), induced by the topical application of amino-levulinic acid (ALA) or its derivatives, ALA methyl-ester (m-ALA), is a treatment for superficial basal ...
Elsevier2008Autofluorescence detection of tumors in the human lung - spectroscopical measurements in situ, in an in vivo model and in vitro
Georges Wagnières, Tanja Gabrecht
To detect bronchial carcinoma by autofluorescence, we measured the spectra of tumor and normal tissue in situ, in an in vivo model and in vitro by fiber optic spectrometer and two-dimensional resolved microspectroscopy. The in situ measurements were perfor ...
Elsevier2008Low-frequency electromagnetic field effects on functional groups in human skin keratinocytes cells revealed by IR-SNOM
Giorgio Margaritondo, Dusan Vobornik
Human HaCaT cells, exposed for 24 h to a 1 mT (rms) 50 Hz sinusoidal magnetic field in a temperature-regulated solenoid, suffer detectable changes in their biochemical properties and shapes. By using infrared wavelength-selective scanning near-field optica ...
2008Ruthenium Porphyrin Compounds for Photodynamic Therapy of Cancer
Paul Joseph Dyson, Wee Han Ang, Frédéric Schmitt
Five 5,10,15,20-tetra(4-pyridyl)porphyrin (TPP) areneruthenium(II) derivs., a p-cymeneosmium, a pentamethylcyclopentadienyliridium and a pentamethylcyclopentadienylrhodium analog were prepd. and characterized as potential photosensitizing chemotherapeutic ...
2008Label-free detection of DNA with interdigitated micro-electrodes in a fluidic cell
We investigate the analytical performance of an interdigitated electrode sensor for the label-free detection of DNA, by monitoring the complex impedance of 5 µm wide interdigitated Pt microelectrodes on a glass substrate. We detect the hybridization of unl ...
2008Detection of early bronchial cancer by autofluorescence: Results in patients with H&N cancer
Hubert van den Bergh, Georges Wagnières, Matthieu Philippe Emmanuel Zellweger, Tanja Gabrecht, Blaise Lovisa
Head and neck (H&N) cancer patients have a high incidence of second primary tumors in the tracheobronchial tree. Diagnostic autofluorescence endoscopy (DAFE) has shown promising results in the detection of early neoplastic and pre-neoplastic changes in the ...
2007Clinical fluorescence spectroscopy and imaging for the detection of early carcinoma by autofluorescence bronchoscopy and the study of the protoporphyrin IX pharmacokinetics in the endometrium
The aim of this thesis is to optimise and gain fundamental information on two applications of photomedicine using fluorescence imaging and spectrofluorometry: (1) the detection of early bronchial cancer by autofluorescence imaging and (2) the endometrial a ...
EPFL2006